A study of correlation between Platelet Volume Indices (PVI) in patients of Dyslipidemia in tertiary care hospital
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2018, Vol 4, Issue 4
Abstract
Background: The dyslipidemia is a risk factors for cardiovascular disease. Ischemic heart disease is the leading cause of death world wide. Platelet volume reflects platelet reactivity and has been suggested as an independent risk factor for ischemic events in cardiovascular disease. We have shown preliminary results on production of larger platelets by Mean Platelets Volume (MPV) and Platelets Distribution Width (PDW) determination in a group of patients with lipid profile abnormalities. Materials & Method: The study was performed in patients coming to GMERS Medical College, Junagadh from June 2016 to December 2017. Blood sample was collected in plain tube for lipid profile analysis, EDTA vaccutainer for haematological analysis. PVI were obtained by using Horriba 5 part auto mated cell counter & Lipid profile parameters by fully automated analyzer Roche’s COBAS INTEGRA 400plus. Results: our study comprising of 500 patient’s samples and 50 control samples, In patient’s group high levels of total cholesterol correlates more with high value of PDW than with MPV. Conclusion: PVI like MPV and PDW are strongly associated with dyslipidemia. The estimation of these PVI can be considered as an early, economical and rapid procedure for identification of complication sin hyper lipidemic patients.
Authors and Affiliations
Alpesh M. Maru, Mayur Jitubhai Kokani
Keywords
Related Articles
- EP ID EP376480
- DOI 10.17511/ jopm. 2018.i4.03
- Views 118
- Downloads 0
Ovarian mass lesions: evaluation of ultrasound guided fine needle aspiration cytology with histopathological correlation
Background: Ovarian masses are frequent finding in females of reproductive age group. Image-guided fine-needle aspiration cytology (FNAC) of ovarian lumps is being increasingly used for the successful diagnosis of ovaria...
Primary squamous cell carcinoma of breast: A Rare Case Report
Primary squamous cell carcinoma (SCC) of breast is a pure epithelial type of metaplastic carcinoma accounting for less than 0.1% of all breast cancers. A 70 year female presented with left breast lump of 4 months duratio...
The use of molecular markers (Ki67 & p53) in premalignant and malignant cervical neoplasms
Introduction: Cervical cancers are the second most frequent type of cancer in females. It develops from premalignant to invasive stages in a multistep process of carcinogenesis. The differentiation between cervical intra...
Isolated intramuscular histoplasmosis in an elderly - diagnosis by fine needle aspiration cytology
Background: Histoplasmosis is a mycotic infection commonly affecting patients with impaired immunity. It mainly manifests as pulmonary or disseminated infection. The diagnosis is often missed in non-endemic regions due t...
Pathological and Microbiological Analysis of Cerebrospinal Fluid in Bacterial Meningitis
Background: Meningitis is a life threatening infection with incidences increasing in adults and children. CSF analysis is a key tool to diagnose and differentiate between bacterial, viral, tubercular and fungal meningiti...