A study of correlation between Platelet Volume Indices (PVI) in patients of Dyslipidemia in tertiary care hospital
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2018, Vol 4, Issue 4
Abstract
Background: The dyslipidemia is a risk factors for cardiovascular disease. Ischemic heart disease is the leading cause of death world wide. Platelet volume reflects platelet reactivity and has been suggested as an independent risk factor for ischemic events in cardiovascular disease. We have shown preliminary results on production of larger platelets by Mean Platelets Volume (MPV) and Platelets Distribution Width (PDW) determination in a group of patients with lipid profile abnormalities. Materials & Method: The study was performed in patients coming to GMERS Medical College, Junagadh from June 2016 to December 2017. Blood sample was collected in plain tube for lipid profile analysis, EDTA vaccutainer for haematological analysis. PVI were obtained by using Horriba 5 part auto mated cell counter & Lipid profile parameters by fully automated analyzer Roche’s COBAS INTEGRA 400plus. Results: our study comprising of 500 patient’s samples and 50 control samples, In patient’s group high levels of total cholesterol correlates more with high value of PDW than with MPV. Conclusion: PVI like MPV and PDW are strongly associated with dyslipidemia. The estimation of these PVI can be considered as an early, economical and rapid procedure for identification of complication sin hyper lipidemic patients.
Authors and Affiliations
Alpesh M. Maru, Mayur Jitubhai Kokani
Keywords
Related Articles
- EP ID EP376480
- DOI 10.17511/ jopm. 2018.i4.03
- Views 121
- Downloads 0
Histomorphological spectrum of salivary gland tumors: a study at tertiary care teaching hospital of North Gujarat
Background: Salivary gland tumors (SGTs) are rare neoplasm of head and neck region. The salivary gland tumours vary widely in histopathological appearance. Also, epidemiological data of these tumors in various parts of t...
Incidence of H1N1 in pediatric population in a tertiary care hospital in Bangalore
Objectives: Influenza viruses continue to be a major health threat in both endemic and pandemic forms. The rapid, continuous, and unpredictable nature of influenza viral evolution makes vaccine strategies and pandemic pl...
Correlation of coronary artery atherosclerosis typing and luminal narrowing with ischemic myocardial lesions in post mortem heart specimens: a four year retrospective study
Introduction: Atherosclerosis accounts for a large proportion of cardiovascular system associated morbidity and mortality. Coronary artery disease (CAD) is the leading cause of global deaths with about 80% of burden occu...
Lichen Planus – A clinical and histopathological correlation
Introduction: History and characteristic examination findings are often sufficient to diagnose cutaneous lichen planus. Although lichen planus has distinctive clinical features, the diagnosis may present a problem due to...
Intraorbital, extraconal cavernous hemangioma: a common tumor at an uncommon site-a case report
A wide variety of processes can produce space occupying lesions in and around the orbit including benign neoplasms, malignant neoplasms, vascular lesions, inflammatory diseases, congenital lesions etc. Cavernous hemangio...