A study of correlation of serum lipid profile in patients with hypothyroidism
Journal Title: International Journal of Medical Science and Public Health - Year 2015, Vol 4, Issue 8
Abstract
Background: Hypothyroidism is a common problem that reduces the functional ability of life. Hypothyroidism is associated with altered lipid levels, which increases the cardiovascular risk. Objective: The objectives of this study were to study whether there is any correlation between serum lipid levels and hypothyroidism (subclinical and overt) in a rural population of Gujarat and to study whether there is any difference in lipid levels among menopausal and postmenopausal women. Materials and Method: A cross-sectional study was conducted at Clinical Biochemistry department, P.S. Medical College, Karamsad, which consisted 100 hypothyroid patients (subclinical and overt) and 100 similar age- and sex-matched controls. Serum total thyroxine, triiodothyronine, thyroid-stimulating hormone, free thyroxine, serum cholesterol, triglyceride, high-density lipoprotein (HDL) and low-density lipoprotein levels were examined in subclinical and euthyroid patients. Results: In patient with subclinical hypothyroidism, we found elevated serum total cholesterol (217.95) and triglyceride (148.35) levels as compared to controls ( P = 0.001) but statistically insignificant HDL level (51.45; P = 0.973). In patient with overt hypothyroidism, elevated serum total cholesterol (271.92) and triglyceride (166.31) were found as compared to control ( P = 0.001), but HDL level (46.57; P = 0.134) was found to be decreased. Conclusion: There is association between subclinical and overt hypothyroidism with dyslipidemia. This might be a potential risk factor for coronary artery disease.
Authors and Affiliations
Janki Pinakin Desai, Uday N Vachhani, Gaurav Modi, Kiran Chauhan
Keywords
Related Articles
- EP ID EP111761
- DOI 10.5455/ijmsph.2015.18032015234
- Views 95
- Downloads 0
Application of the “rule of halves” for hypertension as an assessment tool in an urban and rural population at Shimoga, Karnataka - A cross-sectional study
Background: Hypertension is a challenging disease in the developing countries like India as majority of the cases remain undiagnosed and hidden in the community. Therefore the disease hypertension adheres to “rule of hal...
Comparison of development of sputum positive pulmonary tuberculosis in controlled and uncontrolled 50 cases of diabetes mellitus
Background: Tuberculosis (TB) is one of the prominent preventable and treatable causes of death in developed country. Diabetes mellitus (DM) is chronic metabolic disorder and have rising trend of incidence and prevalence...
Scrotal sonography in early management of subclinical varicocele and male infertility
Background: Varicocele is the most common cause of male infertility. About 20 – 30% men with varicocele are infertile. The clinically obvious varicocele is identi fi able and correctable cause of male infertility,...
Assessment of airborne infection control practices in the pulmonary medicine ward in a tertiary-care hospital of south Gujarat
Background: Airborne transmission of infectious diseases is a major public health concern. This airborne transmission becomes even more prevalent in health-care settings because of overburdened hospitals and the pres...
Study of association of ABO blood group with ischemic heart disease
Background: Increasing use of blood group distribution in the study of diseases has prompted us to use this technique in an attempt to assess the role of genetic factor in development of ischemic heart disease (IHD)....