A STUDY OF DEPRESSION IN DIABETES AND THE RELATION OF DEPRESSION WITH GLYCAEMIC CONTROL AND DISEASE ACCEPTANCE

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A STUDY OF DEPRESSION IN DIABETES AND THE RELATION OF DEPRESSION WITH GLYCAEMIC CONTROL AND DISEASE ACCEPTANCE

Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 45

Abstract

BACKGROUND Presence of psychiatric illness like depression may affect diet, exercise or drug management of diabetic patients. A review of 20 studies showed 15% prevalence of depression in diabetes. Psychological factors like abnormal coping skills by avoiding negative thoughts and feelings related to diabetes may lead to higher levels of depression, poor quality of life and poor adherence to medication. Even though the prevalence of diabetes is high in this part of the world, studies related to above factors are rare. MATERIALS AND METHODS A cross-sectional study to find the prevalence of depression and its relation to blood sugar control and disease acceptance. Patients satisfying WHO criteria of diabetes, with age more than 35 and duration of diabetes less than 5 years and without having other severe physical illness or mental retardation were studied by using MINI neuropsychiatric inventory, MADRS and AADQ. RESULTS Among the 320 diabetic patients examined, psychiatric diagnosis was present made 122 (38.1%) and out of this, depression was present in 64 patients (20%). 58 patients with a psychiatric diagnosis other than depression were excluded from the analysis to avoid the confounding variables. The remaining 262 patients were analysed. Among the depressive patients, 26 (40.6%) had mild depressive episode, 28 (43.8%) had moderate depressive episode and 10 (15.6%) had severe depressive episode. Out of the 38 patients in ‘without dietary modification’ group 22 showed depressive disorder, which is significant (p value 0.000). Among the 14 patients with diabetic complications depression was present in 8 patients, significant relation with p value 0.003. Among the 157 patients with combined treatment (both OHA and insulin) depression was present in 50 patients, significant relation with p value 0.003. Mean HbA1C in depressed group was 10.575 and non-depressed group was 8.641, significant statistically with p value 0.000. Mean AADQ score in depressed group was 42.14 and in non-depressed group was 59.22. There was significant difference between the group. AADQ values had significant negative correlation with HbA1C and there was statistically significant positive correlation between HbA1C and severity of depression. CONCLUSION Depression is a common comorbidity in diabetes mellitus (20%). Low acceptance of diabetes is related to depression and the severity of depression is positively correlated with HbA1C values.

Authors and Affiliations

Shynu Raju, Ramash K

Keywords

Depression Diabetes HbA1C and Acceptance.

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EP ID EP549325
DOI 10.14260/jemds/2018/1090
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