A STUDY OF DIASTOLIC DYSFUNCTION IN PATIENTS OF TYPE-2 DIABETES MELLITUS IN RURAL POPULATION OF WESTERN UTTAR PRADESH
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 27
Abstract
BACKGROUND Diabetes mellitus is a disease with multisystem involvement. Most common cardiovascular complications of diabetes mellitus is the presence of diabetic cardiomyopathy. Diastolic left ventricular dysfunction may be early sign of diabetic cardiomyopathy, which is easily accessed by echocardiography. The aim of the study is to study the prevalence of left ventricular diastolic dysfunction (LVDD) in asymptomatic, nonhypertensive patients of diabetes mellitus. MATERIALS AND METHODS A study was carried out on 110 diabetic patients. All the patients were subjected to detailed history, physical examination and specific investigations were done to find out the prevalence of diastolic dysfunction. RESULTS Diastolic dysfunction was present in 79.10% of patients. Diastolic dysfunction was present more in female than male (52.88% vs. 47.12%). Grade 1 diastolic dysfunction was the commonest form of diastolic dysfunction followed by grade 2 and grade 3. Diastolic dysfunction was positively correlated with HbA1c level (r=0.191, p=0.046), duration of diabetes (p-value <0.05, r=0.651) and advancing age (r=0.505, p<0.05). CONCLUSION Echocardiography is a sensitive method to investigate for diastolic dysfunction. There is a high prevalence of diastolic dysfunction in diabetes, which is an early marker of diabetic cardiomyopathy.
Authors and Affiliations
Manoj Kumar, Rajesh Kumar Gautham, Prem S Singh, Granth Kumar, Priyesh Kant, Himanshu Sharma, Tony Pious
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