A study of effect of gastric lavage on meconium aspiration syndrome and feeding tolerance in vigorous infants born with meconium stained amniotic fluid
Journal Title: MedPulse -International Medical Journal - Year 2019, Vol 6, Issue 2
Abstract
Objective: To compare the incidence of meconium aspiration syndrome and feed intolerance in infants born through meconiumstained amniotic fluid with or without gastric lavage performed at birth. Design: Parallel group unmasked randomized controlled trial. Participants: 700 vigorous infants of gestational age ≥34 weeks from through meconium stained amniotic fluid. Intervention: Gastric lavage in the labor room with normal salineat 10 mL per kg body weight (n=350) or no gastric lavage (n=350). Meconiumcrit was measured and expressed as ≤30% and >30%. Outcome Measures: Meconium aspiration syndrome, feed in to lerance and procedure-related complications during 72 h of observation. Results: 5 (1.4%) infants in lavage group and 8 (2.2%) in nolavage group developed meconium aspiration syndrome (RR0.63, 95% CI 0.21, 1.89). Feed intolerance was observed in 37(10.5%) and 53 infants (15.1%) in lavage and no lavage groups, respectively (RR 0.70, 95% CI 0.47, 1.03). None of the infants in either group developed apnea, bradycardia or cyanosis during the procedure. Conclusion: Gastric lavage performed in the labor room does not seem to reduce either meconium aspiration syndrome or feed in to lerance in vigorous infants born through meconium stainedamniotic fluid.
Authors and Affiliations
Mani Shankar, Ashok Kumar
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