A study of effect of Vitamin D supplementation in Osteoarthritis patients
Journal Title: Surgical Update: International Journal of Surgery and Orthopedics - Year 2018, Vol 4, Issue 2
Abstract
Introduction: Osteoarthritis (OA) is the common cause of musculoskeletal disability and pain. Osteoarthritis (OA) is a chronic disease characterized by a loss of articular cartilage and changes of the subchondral bone. Lower levels of vitamin D were associated with greater knee pain, poor quadriceps function with poor physical function. Several studies have documented that vitamin D supplementation increases muscle strength, improve physical performance, and decreases risk of falls among older people with low level of serum vitamin D. Materials &Methods: This present study was conducted at the outpatient clinic of the Department of Orthopedics at Maheswara Medical College & Hospital, Sangareddy during a February–December 2017 study period.The inclusion criteria were that the participants had symptomatic knee OA and low vitamin D status (25(OH)D < 30 ng/mL). Results: Data were analyzed using SPSS Statistics version 22 (SPSS, Inc., Chicago, IL, USA). Comparisonof baseline vs. post-vitamin Dsupplementation data was performed by paired t-test. One-way repeated-measurement ANOVA was used to test the time differences in muscle strength and physical performance. A p-value less than 0.05 for differences and the values were considered to be statistically significant. Dominant grip strength (p = 0.01) and overall physical performance, such as gait speed (p < 0.001), TUGT (p < 0.001), STS (p < 0.001), and 6MWT (p < 0.001), significantly improved after vitamin. Conclusion: Nevertheless, vitamin D supplementation is a safe and inexpensive way to improve muscle strength and physical function in this population. Based on these findings, we recommend vitamin D supplementation in knee OA patients that have poor physical function.
Authors and Affiliations
J. Ashok Vardhan Reddy, Sridhar Garikapati
Keywords
Related Articles
- EP ID EP506006
- DOI 10.17511/ijoso.2018.i2.06.
- Views 143
- Downloads 0
Comparitive study between stretching exercises and corticosteroid injection in treatment of patients with plantar fasciitis
Introduction: Plantar fasciitis is the commonnest cause of heel pain. Its cause is uncertain so as there is a lot of treatment methods for it. Our study compares the outcome of two common treatment modaliy known as local...
Peri-operative hyponatremia in orthopaedic injury patients
Introduction: Hyponatremia is a common electrolyte disorder, particularly in orthopeadic trauma surgery patients and associated with adverse clinical outcomes. The aim of the study is to define the patient demographics,...
A clinical study of laparoscopic versus open umbilical hernia repair
become the standard of practice for inguinal hernia management, the same has been adapted for Umbilical hernia management with better outcome. There is still debate going on regarding the better surgical approach. There...
Unusual presentation of follicular thyroid carcinomaas mandibular metastasis
Primary carcinoma of thyroid presenting as mandibular metastasis is a rare incidence. Most of the time patient presents with various other symptoms due to hematogenous spread of primary neoplasm. We are presenting a rare...
A comparative study between plating & intramedullary nailing for displaced diaphyseal fractures of radius and ulna in adults
Background: In the current era of industrialization and with mechanized farming in India, fractures of forearm bones have become more common. The forearm serves an important role in the functioning of the upper extremity...