A Study of Effectiveness of Intralesional Vitamin D3 in Treatment of Multiple Cutaneous Warts
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
VerrucaVulgaris (viral warts) is a fairly common condition with manytherapeutic options having variable success rates. Few warts are refractory to treatment with often disappointing response and high recurrence. Intralesional immunotherapy has gained importance due to its effectiveness in clearing both treated and distant warts by stimulating the cell-mediated immunity against human papillomavirus. Aims and objectives: This study aims to evaluate the effectiveness and safety of intralesional Vitamin D3 injections in the treatment of multiple cutaneous warts. Materials and Methods: Patients with multiple cutaneous warts were selected and Vitamin D3 (0.2-0.4 ml, 15 mg/ml) was injected at the base of warts. The injections were repeated at an interval of3 weeksfor a maximum of 4 sessions or until complete clearance, whichever was earlier. A maximum of 5 warts was treated in one session and patients were followed up for a period of 6 months after the last injection. Results: Sixty patients with multiple cutaneous warts were included in the study who completed the 6-month follow-up period and were available for analysis. Of these, 36 had palmoplantar warts, 12 had verruca vulgaris,6 patients had periungual warts and 6 patients had filiform warts. In total, 48 of 60 patients (80%) showed a complete response, 6 patients (10%) showed moderate response and 6 patients (10%) showed a mild or no response. Recurrence was seen in 4 patients. No serious adverse effects were reported. Conclusion: Intralesional Vitamin D3 is effective and safe for the treatment of multiple cutaneous warts.
Authors and Affiliations
Dr. M. NARESH
Keywords
Related Articles
- EP ID EP554790
- DOI 10.9790/0853-1803058487.
- Views 68
- Downloads 0
Short implants in clinical practice
Over time, progressively shorter implants have been placed such that short implants are now available that are less than 6 mm in length. The viability and high success rates seen with short implants can be explained by o...
Functional Outcome of Bimalleolar Ankle Fractures Treated With Semitubular Plate for Lateral Malleolus and Malleolar Screws for Medial Malleolus
Background: Malleolar injuries are the most common significant lower extremity fractures. These injuries gain importance, because the whole body weight is transmitted through the ankle, and locomotion depends on the stab...
Study of various Psychiatric comorbidity in Alcohol Dependent Males in Tertiary Centre.
Background: Alcoholics have been associated with various Psychiatric comorbid disorderwhichhave a poorer prognosis and affects treatment outcome as well Aim: To study the various Psychiatric comorbidity in alcohol-depend...
Pseudohypoparathyroidism: A Rare but Important Cause of Hypocalcaemia A Case Report
.
Optimizing Esthetics with Ceramic Veneers: A Case Report
Veneers are the most frequently prescribed aesthetic restorations today. Ceramic veneers can be offered as the treatment option in a wide variety of different cases such as correcting tooth defects, abrasion, orthodontic...