A Study of Efficacy ofBotulinum Toxin Type A in Treatment of Hyper salivation
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 8
Abstract
Abstract: Hyper salivation or drooling is unintentional loss of saliva from the mouth,seen usually in patients with neurological deficits such as cerebral palsy, motor neuron disease or Parkinson’s disease. Persistent drooling may cause problems in social development of patients, as well as problems related to personal hygiene. Many studies have investigated the clinical improvement in drooling after the injection of botulinum toxin type A (BTXA). Our present study was performed in cerebral palsy patients in whom we followed a simplified procedure of Injecting Botulinum toxin in children of cerebral palsy at lower doses than other study. USG studies were not carried out and injections were given based on anatomy and palpation of the gland which is superficial. Fourteen cerebral palsy patients (6-15 years-of-age; mean 08yrs, 08 boys and 06 girls) were injected with 0.5 units/kg body weight of Botulinum Toxin Type A in each parotid. Three injections with an insulin syringe were given in each parotid. Children were followed up weekly for first four weeks and thereafter monthly. Twelve children out of fourteen showed improvement following BTXA injections, thus demonstrating that Botulinum Toxin Type A injection is an effective treatment of hyper salivation. Keywords:Hyper salivation, Drooling, Botulinum Toxin.
Authors and Affiliations
DrArun Tyagi, Dr Sanjay I Totlani
Keywords
Related Articles
- EP ID EP371827
- DOI -
- Views 36
- Downloads 0
Comparison of Surgical Outcome Between Anterior Cervical Discectomy and Fusion (ACDF) with Transcorporeal Anterior Cervical Microforaminotomy for Brachalgia
Anterior Cervical Discectomy and Fusion (ACDF) is generally performed for brachalgia and is linked with significant complication such as spinal cord injury recurrent laryngeal palsy, infection or swallowing issue. The An...
A Survey of the Prevalence of Hepatitis B and Hepatitis C Antibodies amongst HIV Positive Patients in Tertiary Health Institution in South Eastern Nigeria
Human immunodeficiency virus is a major pandemic in Nigeria and the growing prevalence of hepatitis of Hepatitis B and C admix infection in on increasing measure. A survey on the prevalence of hepatitis B and C amongst H...
Hepatitis C Virus (HCV) Genotyping and its Clinical Utility for Disease Monitoring
The hepatotropic viruses are a major public health problem representing the most common cause of liver disease worldwide. The distribution of HCV genotypes vary according to the geographical region. Genotypes 1-3 are wid...
A Study of Clinical Profile of Systemic Anaphylaxis in Honey Bee Sting Reactions
The members of the Hymenoptera order are honey bees, wasps, hornets, yellow jackets and ants which are frequently involved in accidental stings to human beings. Bee venom consists of a mixture of biologically active subs...
A study on pharmacovigilance awareness among the healthcare professionals in a tertiary hospital, Imphal
Spontaneous adverse drug reaction (ADR) reporting by health professionals is the corner stone of ADR monitoring activity of National Pharmacovigilance Programme. Present study was designed to assess the knowledge, attitu...