A STUDY OF HIGH DOSE VERSUS LOW DOSE FUROSEMIDE THERAPY IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 26
Abstract
BACKGROUND In cases of Acute Decompensated Heart Failure (ADHF) Loop diuretics are an important component of current treatment and are administered to approximately 90% of patients who are hospitalized with heart failure1 . Despite decades of clinical experience with these agents, there are few studies to guide their use. MATERIALS AND METHODS Total 60 patients included in the study (30 in each group), were randomized into two groups – High dose and Low dose furosemide therapy group. Following were considered as the end points, negative fluid balance at 24 hours after admission, duration of hospital stay, trend of serum electrolytes, clinical outcome (death and hospital re-admission). RESULTS We noticed that there was significant diuresis in the first 24 hours and shorter hospital stay in high dose diuretic group. There was no significant difference in serum sodium and potassium levels and hospital re-admission. There was significant difference in the renal parameters with transient elevation in serum urea and creatinine, seen in high dose group as compared to low dose group. CONCLUSION Both high dose and low dose diuretic modality of treatment have equal role in the management of ADHF. High dose diuretic strategy has been associated with shorter hospital stay and rapid improvement in clinical symptoms so, it might be effective diuretic strategy.
Authors and Affiliations
Rajkumar Gurulingayya Hiremath, Durgaprasad Mallappa Kabade, Prashant Kumar Malkiwodeyar, Ameet Vasanthrao Khatawkar, Jagdeesh Gangadhar Mahajanshettar, Ganeshgouda Majigoudra, Veeresh Basavaraj Hubballi
Keywords
Related Articles
- EP ID EP567161
- DOI 10.18410/jebmh/2018/414
- Views 53
- Downloads 0
A COMPARATIVE STUDY OF CORONARY ARTERY DISEASE IN PREMENOPAUSAL WITH POSTMENOPAUSAL WOMEN
Coronary artery disease though more common in postmenopausal women, is not uncommon in premenopausal women especially in those having non-conventional risk factors. MATERIALS & METHODS: All women who underwent coronary a...
ENDOSCOPIC DCR A COMPARATIVE STUDY BETWEEN CONVENTIONAL MUCOSAL FLAP, MITOMYCIN C APPLICATION AND SILICONE STENTING
BACKGROUND/OBJECTIVES: Recurrent stenosis and closure of neostium is considered a major factor for surgical failure in endoscopic dacryocystorhinostomy (Endo DCR). The main objective of this study is to evaluate the role...
PENETRATING INJURY ABDOMEN: A STUDY AT GOVERNMENT GENERAL HOSPITAL
Penetrating injuries to the abdomen form an important chunk of surgical problems confronting the trauma surgeon. These injuries usually affect young healthy individuals in the society. Previously all abdominal penetratin...
ATTENUATION OF CARDIOVASCULAR RESPONSES TO LARYNGOSCOPY AND INTUBATIONDEXMEDETOMIDINE VS. MAGNESIUM SULFATE
BACKGROUND Laryngoscopy and intubation are associated with cardiovascular changes like tachycardia, increase in blood pressure and pulmonary artery pressure and arrhythmias and ever since several methods have been sugges...
TWO NEWER METHODS OF PTERYGIUM SURGERY- A COMPARATIVE STUDY
BACKGROUND This study aims to evaluate the surgical treatment of pterygium by pterygium excision with conjunctival autografting without glue without sutures and preoperative subconjunctival injection of 5-fluorouracil wi...