A Study of Infective Endocarditis in Valvular Heart Disease in North East India
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Introduction: Infective Endocarditis (IE) is disease caused by infection of endothelial lining of intra-cardiac structures and is invariably fatal, if untreated. Objectives: To study the incidence, clinical profile, microbiological profile of Infective Endocarditis in Valvular Heart Failure. Methods: We conducted a hospital-based Observational Descriptive study comprising of 150 patients of Valvular Heart Disease from July 2015 - June 2016 who were diagnosed on basis of thorough history, physical examination, Echocardiography, Blood Culture testing, etc. by application of Modified Dukes Criteria. The patients were admitted in Gauhati Medical College and Hospital, Assam, India and fulfilled the Inclusion and Exclusion criteria of the study. Statistical analysis was performed by Fisher’s Exact or Chi-Square Test. Results: In our study, 22 out of 150 patients (14.67%) were confirmed to have Infective Endocarditis and the further results and observation were made out of these Definitive cases. Majority of cases (40.91%) were in their fourth decade. 72.73% cases were male. The origin was mostly rheumatic (77.27%). Fever and Congestive Heart Failure were the predominant symptom and complication respectively. Vegetation’s were observed in 90.91% cases. 35 % of cases had >/= 10 mm vegetation size, and they had more complications. Mitral valve (36.36%) was the predominantly involving valve. Blood culture positivity was 36.36%. Staphylococcus aureus (50%) was the most common organism isolated. All organisms were sensitive to Vancomycin and Linezolid. Mortality was 13.64%. Discussion: IE is more common in Rheumatic heart disease. In Indian scenario, more emphasis should be given on Echocardiography in diagnosing IE. The predominant organism is Staphylococcus aureus, sensitive to Vancomycin and Linezolid.
Authors and Affiliations
Tribeni Sharma, Debabrata Goswami, Rajarshi Chakraborty
Keywords
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- EP ID EP539115
- DOI 10.21276/ijmrp.2018.4.2.043
- Views 81
- Downloads 0
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