A study of Leprosy cases: Correlation of clinical features, histopathology and demonstration of Lepra bacilli.
Journal Title: BJKines-National Journal of Basic & Applied Science - Year 2017, Vol 9, Issue 2
Abstract
Introduction: The clinical manifestations of leprosy are too varied and diverse and can mimic variety of unrelated diseases. In patients of leprosy the treatment plan differs depending on histopathological subtype and bacillary load. This study aims to decide the incidence of various histopathological subtypes of leprosy and to correlate the clinical subtyping of all suspected cases of leprosy, with their histopathological subtyping &findings of modified Fite Faraco staining to demonstrate Lepra bacilli. Materials and Methods: The present study was conducted at Department of Pathology, P. D. U Medical College, Rajkot, Gujarat, for the period of 2 years from August 2014 to Sept 2016.Skinbiopsies from all patients clinically suspected as leprosy were studied to confirm the diagnosis, to classify histopathologically, and to know bacillary load by Fite Faraco staining. The clinical features, histopathological features and Fite Faraco stain findings were then correlated. Results: Out of 182 Biopsies from suspected cases of leprosy, 171 were confirmed as leprosy on histopathology. Peak incidence was in 21- 30 years of age group, while M: F ratio was 1.75:1.Maximum number [24.7%] of cases were of lepromatous leprosy (LL). Overall clinicopathological parity in various types of leprosy was observed in 67.4% of cases. Modified Fite Faraco stain positivity was observed in64.3 % cases. Conclusion: Leprosy is still prevalent in the region of study, Lepromatous Leprosy being the commonest. Proper histopathological diagnosis with subtyping and demonstration of lepra bacilli on tissue sections are very important in clinical management of all leprosy cases.
Authors and Affiliations
Dr. Shilpa Taviyad, Dr. Milan Purohit, Dr. Trupti Purohit, Dr. Gauravi Dhruva
Keywords
Related Articles
- EP ID EP255639
- DOI -
- Views 112
- Downloads 0
A case report of Ophthalmic Myiasis in an urban setting.
Myiasis is the infestation of the tissues and organs of animals or man by fly larvae. Oestrosis is a regional myiasis caused by larvae of the fly Oestrus ovis which belongs to class Insecta, order Diptera and family Oest...
Study of Alterations in Lipid Profile After Burn Injury.
Introduction: After burn injury, changes in lipid profile occur in body. Dyslipidemia after burn injury is one of the important alterations. Objective: To check alterations in lipid profile after burn injury. Materials a...
Anatomical Variation of Human Sacral Hiatus Its Morphometry and Clinical Importance in Caudal Epidural Anesthesia.
Introduction: The sacrum is a bone which contributes to the formation of the pelvic girdle. It has piqued the interest of anatomists, forensic scientists and physicians, especially anaesthetists because of its unique val...
Study of Interparietal (Inca) bone in dry human skulls
Introduction: Squamous part of occipital bone consists of two parts, supraoccipital and interparietal. Interparietal portion may remain separated from the supraoccipital by a suture, it is then called the interparietal b...
Clinical Study of Epidemiology and Histopathological Correlation of Lid Tumours in Indian Population.
Objective: To study the presentation, pattern of distribution and correlate histopathological examination of lid tumor. Materials and Methods: A prospective study of 50 patients presenting to tertiary referral care centr...