A Study of Microalbuminuria in Non-Diabetic Hypertensive Patients of RIMS, Adilabad

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A Study of Microalbuminuria in Non-Diabetic Hypertensive Patients of RIMS, Adilabad

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 8

Abstract

Microalbuminuria is an important marker of generalized vascular damage and indicator of future cardiovascular complications in hypertensive patients. The amount of microalbuminuria indicates the extent of target organ damage. Early detection of microalbumin in urine may be helpful in the management of hypertension. Aim: The study was designed to determine the prevalence of microalbumin in non-diabetic hypertensive patients and comparison with controls. Methods: This study was performed in the Departments of General Medicine and Department of Biochemistry, Rajiv Gandhi Institute of Medical Sciences [RIMS] Adilabad. The Group A (n=50) was Hypertensive group those with elevated blood pressure reading in three subsequent visits to the hospital were included in the hypertensive group. The height and weight of all the participants were measured with standard equipment and the BMI was calculated. Blood pressure was examined by a standard mercury sphygmomanometer after 5 minutes of rest. Fasting blood samples will be collected in Vacutainer 10ml and serum fasting blood sugar, Serum Electrolytes and lipid profile will be estimated. Microalbumin was determined by immunoturbidimetric method were carried out using ‘Beckman Coulter Au 400’ auto analyzer. Results: The mean age of the hypertensive group was 47.5 ± 6.5 yrs and the mean age of the control group was 45 .5 ± 5.6 yrs. In the hypertensive group, 35 (70%) were male and 15 (30%) were female. In the control group, 38(76%) were male and 12 (24%) were female. The serum albumin was slightly lower in the hypertensive group although not significant. The serum urea concentration of the hypertensive group means values were 33.54 ± 6.54 mg/dl and the control group was 28.25 ± 8.94 mg/dl the p values were found to be significant. 19 (38%) of the patients in the hypertensive group were found to be with microalbuminuria and none of the control group was having microalbuminuria the ‘p’ values were found to be highly significant. Conclusion: Microalbuminuria is an important marker of cardiovascular morbidity and mortality including target organ end damage. In this study, 38% of patients were having microalbuminuria. A patient with increased age and greater duration of hypertension develop microalbuminuria frequently. Microalbumin detection should be done in all the hypertensive patients regularly to monitor control and prevent future complications.

Authors and Affiliations

Dr. D. Pragna

Keywords

Keywords: Microalbuminuria Hypertensive patients.

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