A Study of Miliary Tuberculosis in theCoastal Andhra Pradesh
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 11
Abstract
Abstract: The aim of the study was 1.To study the clinical profile of miliary Tuberculosis 2. To evaluate the treatment response by symptomatology sputum conversion, radiological resolution after 2months and 6months periods 3. To study the complications and incidence of MDR TB in Miliary tuberculosis. This prospective observational study was performed using a data base with 40patients with provisional diagnosis of miliary tuberculosis during the period of Jan 2014to April 2015.The clinico-radiological features, treatment response and incidence of complications including the incidence of MDR-TB were analyzed. In the present study mean age of study population is 41years with male predominance (57.5%).In the present study, duration of symptoms ranged from 10days to 3months. Cough, fever, expectoration, loss of weight, loss of appetite, night sweats are the commonest symptoms. 2cases are with headache and 4cases have abdominal pain. Diabetes mellitus was seen in 5%, HIV in 12.5%cases and chronic kidney disease in 2.5%cases of study population. 97.5%cases were negative for tuberculin skin test (TST) in the study population. All cases had military mottling. Miliary mottling associated with consolidation (2 cases), pleural effusion (6cases), pleural thickening (3case) and 3cases had an associated cavitation. 20cases out of 40(50%)had anemia (<10gmHb%) in the study population. Pancytopenia and leucocytosis were observed in 2.5%of the cases. In the study population 5,out of 40(12.5%)cases were positive for sputum AFB smear. In the study population, all had miliary nodules. Four cases (10%)had associated mediastinal lymphadenopathy; one case (2.5%)had associated left multi-loculated hydro pneumothorax. One case associated with bilateral upper lobe fibrosis, 3cases had associated cavity in upper lobe, two cases (5%)had associated segmental consolidation of both upper lobes, 6 cases (15%)had associated minimal pleural effusions (4on right and 2on left), 1 case (2.5%)had associated granulomas along right chest wall 1,case (2.5%)had associated peri-bronchial nodular pattern and Tree in buds suggesting endo-bronchial spread of TB. In the present study, USG Abdomen was done in all the 40cases. Of which 29(72.5%)were of normal study. Ascites was observed in 4(10%)cases, tubo-ovarian mass in 1case (2.5%0, grade 1RPD in one case and pleural effusion was seen in 6cases (15%).Hepato-splenomegaly was observed in 2cases (5%). Keywords:Miliary Tuberculosis, MDR TB, HIV, Miliary mottling.
Authors and Affiliations
Bharavi Chunduri, Surya Kumari, Kalyan Kumar PV
Keywords
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