A study of prevalence of non-alcoholic fatty liver disease in type 2 Diabetes Mellitus
Journal Title: Panacea Journal of Medical Sciences - Year 2016, Vol 6, Issue 3
Abstract
Nonalcoholic fatty liver disease (NAFLD) is one of the common causes of chronic liver disease worldwide and is an emerging important cause of liver disease in India. In the general Indian population, the prevalence of NAFLD is approximately 9- 30% but much higher estimates are reported in obese and patients with type 2 diabetes mellitus. Total of 185 diabetic and 105 non-diabetic patients were randomly selected from diabetic and medicine OPD. After taking informed consent, all patients undergone history, examination and routine laboratory investigations, LFT, lipid profile, HbA1c, serum ferritin, C-reactive protein and USG. The results of cases and control were compared with unpaired t -test and p value <.05 was considered significant. The study group (n=185) was divided into a NAFLD group (n=102) and a non-NAFLD group (n=83) and nondiabetic control (n=105). The prevalence of NAFLD in DM was 55.68% and in non-diabetic was 20%. The NAFLD was significantly associated with high BMI, waist circumference and waist hip ratio, higher HbA1c, higher triglyceride levels, hypercholesterolemia, low HDL levels. Serum CRP level (p<0.00001) and serum ferritin level (p<0.0001) were significantly high in NAFLD patients with DM-2. This study showed that patients with central obesity, Poor Glycemic control and dyslipidemia are at increased risk of developing NAFLD. Serum ferritin and Serum CRP could be good noninvasive marker for screening of NAFLD in asymptomatic patients.
Authors and Affiliations
Kuldeep Chandel, Sandeep Kumar, Mahak Lamba
Keywords
Related Articles
- EP ID EP241796
- DOI -
- Views 87
- Downloads 0
Psychiatric co-morbidities in patients of dhat syndrome: A cross-sectional study in a tertiary care centre
Dhat syndrome is a culturebound syndrome characterised by inappropriate and excessive distress of losing semen from onersquos body and thereby leading to multiple vague psychological and somatic symptoms It is presumed t...
Serological profile of rheumatoid arthritis in a tertiary care hospital
Rheumatoid Arthritis RA is an autoimmune based inflammatory pathology with involvement of joints that show early morning stiffness alongwith pain resulting in loss of function It usually affects females aged 30 years or...
Anosmia in Elderly: Predictor of Cognitive Impairment
The prevalence of olfactory impairment and cognitive impairment increases with age. Olfactory impairment has been associated with neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease. The p...
Use of smart phone for measuring shoulder rotational range of motion in patients with frozen shoulder: A comparative study
Assessment of shoulder range of motion in patients with frozen shoulder is important aspect for physiotherapist for documentation and to check progression in disease. From long time, goniometer is used as gold standard m...
Correlation of phoria with personality: A pioneering study
The development of concomitant squint is a function of personality trait of a child. It is also a known fact that the personality trait of a child is carried forward to his adult personality. Therefore a hypothesis that...