A study of response to lipid lowering therapy in non-diabetic patients with dyslipidemia at tertiary health care center
Journal Title: Medpulse International Journal of Medicine - Year 2017, Vol 4, Issue 2
Abstract
Background: In spite of considerable advances in the understanding of the pathophysiology of ischemic stroke, therapeutic options, particularly pharmacological agents for prevention and treatment are still limited. Aims and Objectives: To Study of response to lipid lowering therapy in non-diabetic patients with dyslipidemia at tertiary health care center. Methodology: All non-diabetic patients with features of stroke admitted to tertiary care hospital from December 2013 to December 2015 were taken for the study. Data will be collected by means of case record form. All non-diabetic patients of cerebrovascular accidents were enrolled in this study with informed consent and detailed patient information were included into study. The clinical outcome after 3 month was assessed by the Modified Rankin Scale (MRS). The statistical analysis done of paired t-test analyzed by SPSS 19 version software. Result: The change of serum TG after 3 months is 23.6mg/dl and P value is < 0.01 which is highly significant. The change of LDL levels after 3 months is 12.04mg/dl and P value is < 0.01 which is highly significant. The change of HDL levels after 3 months is 2.76mg/dl and P value is < 0.01which is highly significant. The change of VLDL levels after 3 months is 3.72mg/dl and P value is < 0.01which is highly significant.MRS score showed a good clinical outcome with reduction in LDL levels and the corresponding P value is 0.26 and r value of 0.15 which is significant. Conclusion: In the present study there is a significant change in bio-chemical values of lipid profile after treating with statins for a duration of 3 months, but there is no significant improvement in clinical outcome except for LDL. So, it can be concluded that measures to reduce serum LDL levels will be useful in secondary prevention of thrombotic stroke.
Authors and Affiliations
Raju Talawar, Darshna Makwana
Keywords
Related Articles
- EP ID EP240448
- DOI -
- Views 135
- Downloads 0
A study of associated factors of male adult anemic patients at tertiary health care center
Background: Anemia is a global public health problem, at any stage of life Aims and Objectives: To study associated factors of male adult anemic patients at tertiary health care center Methodology: This was a cross-secti...
Study of correlation between dyslipidemia and cerebrovascular accidents in non-diabetic patients at tertiary health care center
Background: According to the Indian Council of Medical Research there were 930,985 cases of stroke in 2004 in India. Aims and Objectives: to Study correlation between dyslipidemia and cerebrovascular accidents in non-dia...
Comparison of handgrip strength between type II diabetic patients and non-diabetic individuals
Background: Diabetes mellitus has attained the status of a global epidemic. It is one of the fastest growing chronic metabolic disorders. Skeletal muscle mass is significantly lower in individuals with diabetes, being wo...
A case of Fahr’s Disease - A bright brain
Background: The term “Farh’s disease” was first coined by Karl Theodore Fahr in 1930. As seen in medical literature, this disease is predominantly autosomal dominant in inheritance as compared to autosomal recessive1.Fah...
A study of various complications of right ventricular infarction at tertiary health care centre
Background: Myocardial infarction was previously thought to be a disease of mainly the left ventricle. Right ventricular infarction was just a pathological entity. Aims and Objectives: To Study various complications of r...