A study of role of thrombocytopenia in the prognosis of the patients with malaria
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 6
Abstract
Introduction: Thrombocytopenia is an early and consistent feature of malaria, but its pathogenesis remains incompletely understood. In falciparum malaria there is increased platelet consumption as evidenced by shortened survival of radio labelled platelets. Aims and Objectives: To Study Role of Thrombocytopenia in the Prognosis of the Patients with Malaria. Methodology: After approval from institutional ethical committee, the present study was cross sectional study was carried out at tertiary care hospital in the urban setting. The study period was 1 year from March 2015 to March 2016. Study population consisted of patient diagnosed as case of malaria and admitted at tertiary care hospital during period of one year, Z-test (Standard Error of Difference Between two Proportion) used for statistical analysis. Result: The majority of the patients were form the age group 30-40 i.e. 26.36% followed by 40-50-20.00%; 50-60-17.27%; 20-30-15.45%; 10-20-10.90%; >60-10.00%. The majority of the patients were Male i.e. 70.90% followed by Females38.18%. All 51 cases of severe malaria had thrombocytopenia and 35 cases of uncomplicated malaria had thrombocytopenia. Out of 26 cases of mild thrombocytopenia 12 (14.16%) cases belongs to severe malaria while uncomplicated malaria consisted of 14 (53.84%) cases. Among 29 cases of moderate thrombocytopenia 14 (48.28%) cases had severe malaria while 15 (51.72%) cases had uncomplicated malaria. Out of 31 cases of severe thrombocytopenia 25 (80.64%) cases had severe malaria while only 6 (19.35%) of uncomplicated malaria had severe thrombocytopenia. Significantly more numbers of cases of severe malaria have severe thrombocytopenia as compared to uncomplicated malaria. (z= 4.96; p<0.001). Conclusion: In our study we have found that more numbers of cases of severe malaria have severe thrombocytopenia as compared to uncomplicated malaria hence it can be concluded that the thrombocytopenia correlates with the severity of the Malaria.
Authors and Affiliations
Rajendra Dhar, Rakesh Thakuriya, Kamal Kumar Jain
Keywords
Related Articles
- EP ID EP207067
- DOI -
- Views 67
- Downloads 0
A study of BMI status and estrogen- progesterone receptors in patients with carcinoma of breast
Introduction: Breast carcinoma is the second most common carcinoma in women and account for 22 % of all female cancer, which is more than twice the prevalence of cancer in women at any other site. Aims and Objective: To...
Pre-contoured LCP Vs TENS in treatment of displaced mid-clavicle fractures: Comparative study
Background: Fracture of the clavicle is a frequently seen injury which represents about 10-15% of all fractures in adults. About 80% of all clavicular fractures involve the middle third of the bone. The present study was...
First year medical undergraduate students’ attitude and perception towards psychiatry
Introduction: The way students perceive the subject and display the attitude towards a subject determines the recruitment in a subject. Hence the study was plannedto assess the attitude and misconceptions towards psychia...
Uteroperitoneal fistula – a rare cause of failure of sterilization
Failed sterilization is uncommon event. Recanalization leading to failure is commonly understood reason for this. Here we present to you a rare case of uteroperitoneal fistula leading to so called sterilization failure.
The incidence and clinical profile of ischaemic heart disease in non-insulin dependent diabetes mellitus
Ischaemic heart disease is defined as “Cardiac disability acute or chronic, arising from reduction or arrest of blood supply to the myocardium in association with disease process in the coronary arterial system. Ischaemi...