A STUDY OF SERUM CK-MB LEVEL IN NON DIALYSED CHRONIC KIDNEY DISEASE PATIENTS
Journal Title: IJAR-Indian Journal of Applied Research - Year 2018, Vol 8, Issue 8
Abstract
Chronic kidney disease is associated with early increased risk of cardiovascular morbidity and mortality. CK-MB the traditional marker for myocardial ischemia loses its specifity in renal failure because of non cardiac source of this enzyme. AIMS:The aim of the study was to measure and compare the level of serum CK-MB in non dialysed chronic kidney disease patients and in healthy controls. MATERIAL AND METHOD: 50 healthy controls and 50 non dialysed chronic kidney disease patients on conservative treatment attending Nephrology department, Gauhati Medical College and Hospital, during September 2015-August 2016 were included in this study. Quantitative analysis of urea, creatinine, CK-MB were done by photometric method. RESULTS: Serum CK-MB levels were significantly higher in the cases as compared to controls (p value <0.0001). CONCLUSION: Non specific modest elevation of CK-MB can cause false positive results in absence of myocardial ischemia in CKD patients. So CK-MB should be interpreted with caution in these patients.
Authors and Affiliations
Dr. Arju Saikia, Dr. Syeda Mohsina Rohman
Keywords
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