A STUDY OF SERUM ESTRADIOL LEVELS IN THE FEMALE POPULATION DURING VARIOUS PUBERTAL STAGES
Journal Title: International Journal Of Advances In Gynaecology - Year 2019, Vol 3, Issue 1
Abstract
OBJECTIVE: This study was designed to determine the normal as well as pathologic levels of estradiol in among Pakistani female population in different pubertal stages as no study has been previously done on this topic. Method: Serum estradiol levels of one hundred thirty one female subjects were evaluated at the Reproductive Physiology laboratory of the NIH, Islamabad, using Microparticle Enzyme Immuno Assay (MEIA) technology of M/s Abbott Laboratories. Subjects were divided in to into prepubertal, peri-pubertal and pubertal stages. Samples from the pubertal stage subjects were taken in the follicular phase. Statistical Analysis: Data were compared using student 't'-test. RESULTS: Mean estradiol levels (mIU/ml) were 65.02+10.46 in the follicular phase, 152.04+302.16 during ovulatory phase (mIU/ml), Luteal phase showed E2 7532.91+1684.40 in the luteal phase. (mIU/ml), which were highly significant (P<0.01).The results revealed that age within the different age groups varied non-significantly, while significant differences were observed in case of pathological groups within the same pubertal stage. CONCLUSION: The study showed that the level of estradiol gradually increased from prepubertal to peri pubertal stage and reached at peak value at puberty stage.
Authors and Affiliations
Madeeha Subhan
Keywords
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