A study of severity of malaria with reference to thrombocytopenia
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 2
Abstract
Introduction: Malarial infection reported as early as 1570 BC from Egypt still at times poses a diagnostic and therapeutic challenge in this modern anti- microbial era . All over the world fever has traditionally been recognized as a cardinal sign of illness and has had negative connotations for patient well-being Aims and Objectives: To Study Severity Of malaria with Reference to thrombocytopenia Methodology: After approval from institutional ethical committee, The present study was cross sectional study was carried out at tertiary care hospital in the urban setting. During The study period was 1 year. Total 105 Patients were included into study. Z-test (Standard Error of Difference Between two Proportion) used for statistical analysis. Result: Among 105 cases 81 (77.14%) cases had thrombocytopenia and 24 (22.86%) cases had normal platelet count. By Fisher’s Exact test, p < 0.001, Among 105 cases 81 (77.14%) cases had thrombocytopenia and 24 (22.86%) cases had normal platelet count. By Fisher’s Exact test, p < 0.001, Significant. All 46 cases of severe malaria had thrombocytopenia and 35 cases of uncomplicated malaria had thrombocytopenia. Out of 26 cases of mild thrombocytopenia 12 (14.16%) cases belongs to severe malaria while uncomplicated malaria consisted of 14 (53.84%) cases. Among 29 cases of moderate thrombocytopenia 14 (48.28%) cases had severe malaria while 15 (51.72%) cases had uncomplicated malaria. Out of 26 cases of severe thrombocytopenia 20 (76.92%) cases had severe malaria while only 6 (23.08%) of uncomplicated malaria had severe thrombocytopenia. Significantly more numbers of cases severe malaria have severe thrombocytopenia as compared to uncomplicated malaria. Conclusion: Severe thrombocytopenia is more commonly associated with severe malaria cases.
Authors and Affiliations
Sanjay B Jagtap, Shyam Toshniwal, Madahvi Kabra
Keywords
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