A STUDY OF THE CLINICAL OUTCOMES ASSOCIATED WITH FLUID OVERLOAD IN CRITICALLY ILL PEDIATRIC PATIENTS
Journal Title: INTERNATIONAL JOURNAL OF PURE MEDICAL RESEARCH - Year 2017, Vol 2, Issue 6
Abstract
Background and aim: Intravenous uid administration is one of the most frequently used therapies provided in hospitals. Daily uid balance have been monitored to determine the incidence of uid overload and its impact on the clinical outcome of the critically ill pediatric patients Methods: Over a 12 month period, all pediatric patients admitted to intensive care unit who completed more than 48 hours in the PICU were included. Data recorded for each patient: percentage uid overload = (uid in minus uid out in liters)/ PICU admission weight in KG x 100 %, demographic and clinical data. Data were entered into SPSS and analyzed in terms of frequency and percentage. Results: 203 subjects were included in the study, median age 9 months, mortality rate 26.1 %, and were divided according to the peak positive uid balance recorded during the admission into 3 groups: group A peak uid overload (PFO) <5%, group B PFO 5-10% and group C PFO>10%. The incidence of uid overload was 54(%), 82(%) and 67(%), in group A, B and C respectively. The incidence of PFO in survivors was 28% and was 47.1% among the non survivors (p=0.025*). PICU length of stay, mechanical ventilation days and the incidence of AKI differed signicantly between the 3 groups (p= 0.002, 0.000 and 0.032 respectively). While vasoinotropic score, need for dialysis and diuretics revealed no statistically signicant difference between the three groups (p=0.054, 0.537 and 0.109 respectively). Conclusions: Fluid overload is a common problem in PICU, with PFO associated with respiratory morbidity, need for mechanical ventilation, PICU length of stay and mortality rates.
Authors and Affiliations
Ahmed Ahmed El- Nawawy, Azza Ahmed Mostafa, Manal Abdelmalik Antonios Barsoum, May Mohamed Adel Atta
Keywords
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