A STUDY OF THE CLINICAL PROFILE OF NEONATES WITH THROMBOCYTOPENIA
Journal Title: Stanley Medical Journal - Year 2016, Vol 3, Issue 3
Abstract
Introduction: In Neonatal Intensive Care Units, neonatal thrombocytopenia is the commonest haematological abnormality. Around 20-40% of neonates admitted to NICU will develop thrombocytopenia and 20% of them will develop severe thrombocytopenia. Subjects & methods: This is a retrospective study of 100 consecutive thrombocytopenic babies irrespective of their underlying illness admitted in the NICU of Government Dharmapuri Medical College Hospital, Dharmapuri from January’ 2014. Results: The study group was divided into two groups based on the severity of thrombocytopenia. There were 71 babies in group I and 29 babies in group II. The male: female sex ratio of the study population was 1.2:1. The study group consisted of 42% of term babies and 58% of preterm babies. Among the severely thrombocytopenic babies in the study group, 45% were term babies and 55% were preterm babies. Among the study group, 68 cases were born extramural. About 31% of preterm babies had severe thrombocytopenia. About half of the babies in the study group were below 2.5 kg. Maternal PIH was significantly associated with thrombocytopenia. Septicemia and Birth asphyxia were the predominant causes of thrombocytopenia in both the groups. In group I the prevalence of mucosal bleed was 12.6% whereas in group II it was 89.7%. The prevalence of septicemia was significantly high in both the groups. The incidence of severe thrombocytopenia was significantly high in gram negative sepsis. In the study group 5 neonates died and the proportion of mortality was significantly high in the severely thrombocytopenic infants. Conclusion: Septicemia and birth asphyxia were the common causes of neonatal thrombocytopenia. The easier and cost effective way to prevent thrombocytopenia and its death is by preventing the occurrence of sepsis and birth asphyxia.
Authors and Affiliations
Rameshbabu B, Kumaravel K. S
Keywords
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