A STUDY OF THYROID DYSFUNCTION IN HIV SEROPOSITIVE PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 10
Abstract
BACKGROUND There has been significant increase in the prevalence of HIV and with use of HAART there has been significant increase in the survival of HIV infected individuals, leading to increased detection of comorbid conditions associated with HIV. HIV infection can lead to involvement of various organs including endocrine glands. Among the endocrine disorders a high prevalence of abnormalities in thyroid function tests is reported. Thyroid functions may be altered in 10-15% of patients. MATERIALS AND METHODS The study has been carried out in 100 patients diagnosed with HIV infection according to NACO guidelines fulfilling inclusion and exclusion criteria, getting admitted to the Department of General Medicine, KIMS, Hubli. The data was collected using pretested proforma meeting the objectives of the study. All patients were investigated for thyroid dysfunction by measuring serum TSH, total T3 and T4. RESULTS Among the 100 patients studied, mean age was 37.84±11.05 years, 50 were male. 22% had overt hypothyroidism, 16 (72.73%) males and 6 (27.27%) females. The thyroid function tests in 100 patients compared with CD4 count and the p value found to be 0.907 not statistically significant. Hence no correlation found between CD4 count with the thyroid dysfunction. CONCLUSION Thyroid function test abnormalities are common among HIV patients, particularly men, most common being overt hypothyroidism and no correlation noted with the CD4 count and hence with severity of HIV disease.
Authors and Affiliations
Triveni Ayyanna, Sanjay Neeralagi
Keywords
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- EP ID EP555308
- DOI 10.14260/jemds/2019/161
- Views 82
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