A study of thyroid lesions with cyto-histologic diagnoses correlation
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 9
Abstract
Background: Fine-needle aspiration cytology (FNAC) is widely used as a diagnostic tool to assess thyroid lesions. This study correlates FNA cytology results with histopathology findings. Objectives: The aim of the present study is to correlate FNAC impression with histopathology diagnoses of thyroid lesions in the dept. of Pathology, Gandhi Hospital, Secunderabad and compare our results with those of literature. Methods: All thyroidectomy specimens – lobectomy / total / sub-total received over a period of 3 years were reviewed and 266 patients identified for inclusion. Data were obtained for FNA diagnosis, demographics, findings on ultrasound, and histologic findings. Results: Among 13 patients with a carcinoma on FNAC, 11 were confirmed on final histopathology. Of 35 patients with “follicular lesion” on FNA, only 15% of cases were verified to be malignant histologically. Only 15% of the 173 cases diagnosed as benign on FNAC were found to have a carcinoma on histopathology. Conclusion: A diagnosis of papillary carcinoma cytologically is highly predictive of thyroid cancer. The predictive value of FNAC drops in case of follicular lesions considerably. However, we found a 15% false positive result occuring in FNAC declared benign lesions.
Authors and Affiliations
K Vijaya Lakshmi, K Rama Devi
Keywords
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