A study on adverse drug reaction associated co-morbid symptoms on newly diagnosed TB patients with and without diabetes mellitus
Journal Title: International Archives of Integrated Medicine - Year 2019, Vol 6, Issue 2
Abstract
Background: The incidence of Tuberculosis and severity increased in immunocompromised state like Diabetes mellitus. When combined with ATT and antidiabetic drugs, the adverse reaction are increased. Aim of the study: To study the incidence of adverse drug reaction associated co-morbid symptoms on newly diagnosed TB patients with Diabetes Mellitus. Materials and methods: 100 cases of newly diagnosed sputum positive pulmonary tuberculosis (50 diabetic and 50 non -diabetic) fitting the inclusion criteria admitted over the period of 2 years from 2016-2017. Subjects were selected from medicine ward, pulmonology ward and Tuberculosis ward under DTC. The diagnosis of Pulmonary tuberculosis was made with clinical presentation and verification by detection of acid fast bacilli under microscope. Results: Among the diabetic population, 28 (28.00%) were received biguanides, 10 (10.00%) were received insulin, and 12 (12.00%) were received sulphonylureas. Among the study population, 28 (28.00%) had peripheral neuropathy, 25 (25.00%) had liver injury, 4 (4.00%) had hypoglycemia, 11 (11.00%) had back pain, and 52 (52.00%) had nausea vomiting. Conculsion: When treating patients with diabetes and TB, there is increased incidence of polyneuropathy and liver toxicity.
Authors and Affiliations
D Vijayaraju, M Manjula
Keywords
Related Articles
- EP ID EP673580
- DOI -
- Views 131
- Downloads 0
Significance of sputum cultures in diagnosis of invasive pulmonary aspergillosis in acute leukemia – A meta analysis
The diagnosis of Invasive Pulmonary Aspergillosis (IPA) and therapy with Amphotericin B appear to improve survival, but the early diagnosis is difficult. There are no pathognomonic clinical findings for IPA. The commones...
Study of factors associated with open defecation in a rural area of Nalanda District
Open defecation has many health hazards. Still, it is rampant in different parts of the country. The present study was conducted to find the prevalence of open defecation and factors associated with this behaviour among...
Incidence of fungal etiology in patients with nasal polyps
Introduction: Nasal polyposis is an inflammatory condition of varied etiology, of which fungal etiology is an important cause. Allergic fungal sinusitis (AFS) now is believed to be an allergic reaction to aerosolized env...
Comparative study on efficacy of Ketorolac in the management of post-operative pain when administered intravenously or intramuscularly
Background: In the earlier periods analgesia was restricted to surgical and immediate postoperative period. However, this was associated with a lot of morbidities to the patient in terms of surgical stress and increased...
Study on Ascitic Fluid Culture and Antimicrobial Sensitivity Profile in Cirrhotic Patients admitted in a Medical College Hospital
Background: Spontaneous bacterial peritonitis is a fatal complication of liver cirrhosis. Ascitic fluid culture is positive in half of the cases. Materials and methods: The present cross-sectional study was conducted upo...