A Study on Association Between Serum Magnesium And Acute Exacerbation of COPD
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background:The course of COPD is associated with exacerbations. There are many factors responsible for exacerbations. According to recent study one of the modifiable risk factor is hypomagnesemia. The purpose of this study is to confirm the association between serum magnesium levels and acute exacerbation of COPD. Aims and objectives:To study the association of serum Magnesium level with acute exacerbation and also to know the relationship between Serum Magnesium levels and frequency of exacerbations. Materials and Methods: The study was conducted among 100 COPD patients in Govt. Stanley Medical College hospital from March 2016 to August 2016. A detailed history was elicited, clinical examination and all required investigations were done in all cases. Patients with age above 40 years only included and patients associated with other conditions producing hypo or hypermagnesemia were excluded from this study. Statistical methods:The data was analysed with the help of software such as SPSS16, Microsoft Excel 2016, MEDCALC and GENSTAT version 9.0. Results: Magnesium was at low level in patients who presented with acute exacerbation, normal in stable COPD patients (P value – 0.002). And number of admissions also more in COPD patients with exacerbations. Conclusion: Hypomagnesemia is seen in COPD patients with exacerbations. And also there was more frequent exacerbations found in patients with Hypomagnesemia. So Magnesium is one of the independent and modifiable risk factor for COPD exacerbation. Exacerbations are common in current smokers than ex smokers. So cessation of smoking will delay the decline in lung function.
Authors and Affiliations
Dr. J. Kanimozhi, Dr. S. M. Sujatha
Keywords
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- EP ID EP262532
- DOI 10.9790/0853-1609110912.
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