A Study on Association of Hypertension with Hyperparathyroidism in Non Diabetic Kidney Disease
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 2
Abstract
80 non-diabetic chronic kidney disease (CKD) cases and 40 non-hypertensive non-diabetic non CKD age matched controls were evaluated. The baseline characteristics of both groups were compared. Student‘t’ test was applied to analyse the characteristics among the 2 groups. The cases were stratified according to JNC VII(Joint National Committee VII)stages and characteristics were analysed using ANOVA(analysis of variance).The mean intact parathyroid hormone(iPTH) of CKD cases was 385.7±287.7 pg/ml and of controls was30.8±13.4 pg/ml(t=7.780;p<0.001) thereby showing a significantly raised iPTH in cases. A statistically significant difference was observed between cases and controls in ionized calcium, phosphorus, urea, creatinine, iPTH and vitamin D. iPTH>300pg/ml independently correlated with hypertension when logistic regression was applied on the variables which showed significant association in univariate assessment with blood pressure.Since iPTH independently correlated with hypertension in non-diabetic CKD patients, reduction of iPTH could lower their blood pressure.
Authors and Affiliations
Dr. S. K Shukla, Dr Rita Shukla, Dr Esha
Keywords
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