A Study on Changing Clinical Profile of Chronic Pancreatitis from a Tertiary Care Centre
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 4
Abstract
Background: Idiopathic chronic pancreatitis (ICP) is the most common etiology of CP in most of the studies in India. However, a change in etiological pattern has been observed recently. Aim: To study the clinical profile of recently admitted cases of CP during last 1 year and to compare them with cases during previous 5 years. Patients and Methods: The clinical profile of 150 cases of CP admitted during past 5 years (Group A) was compared with 31 cases of CP seen during last 1 year (Group B). Results: Both the groups had male preponderance. The mean duration of disease was 3.09 years in Group A and 1.12 years in Group B. Pain was the most common presentation in both groups. Steatorrhea was significantly higher in Group A (37.33% vs. 9.68%) (P = 0.0009). In contrast, ascites (8% Group A vs. 29.23% Group B [P = 0.0009]) and pseudocyst (6.67% Group A vs. 19.35% Group B [P = 0.023]) were more common in Group B. Diabetes at presentation was observed in 22% cases in Group A and 13% in Group B. The most common etiology in Group B was alcohol (55%) which was the cause in 21% in Group A (P < 0.0002), whereas ICP in Group B is significantly lower compared to Group A (48.39% vs. 76.67%, P < 0.0002). 15% in Group A and 6.45% in Group B needed surgery. Conclusions: There seems a recent trend of increase in alcoholic CP in our set up during last 1 year. However, further studies are necessary for a firm conclusion.
Authors and Affiliations
Chitta Ranjan Panda, Bijay Misra, Sambit Kumar Behera, Haribhakti Seba Das, Shivaram Prasad Singh
Keywords
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