A Study on Characterization of Breast Lesions Using Sonomammography and Comparing with Histopathology
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Introduction: The changing lifestyle practices can lead to a higher number of cancer cases. Breast cancer is the most common cancer among women in India. It is very important to identify the palpable breast lump as benign or malignant. Ultrasonography is a commonly used screening imaging modality in breast lumps. The present study aims to find out the accuracy of sonomammography by comparing with histopathology. Materials and Methods: A descriptive study was conducted among female patients for one year. It included 75 female patients above 20 years of age with palpable breast lesions and bloody discharge from the nipple. Patients with advanced carcinoma, previously treated cases and patients with history of previous breast biopsy were excluded from the study. Designed as diagnostic test evaluation, sensitivity, specificity, positive predictive value and negative predictive value of the variables in differentiation was calculated comparing with histolopathological diagnosis. The features of ultrasonography was analyzed by Cohen’s Kappa for statistical agreement with histopathology. Results: With sonomammography, the sensitivity, specificity and accuracy obtained were 83.3%, 89.7% and 86.67% respectively for detection of malignancy. Discussion and Conclusion: Sonomammography is a very useful non-invasive imaging modality having high sensitivity and specificity in diagnosing breast lesions. This study shows that ultrasonography is useful in characterization of breast masses. The requirement of biopsy for breast masses can be reduced. The kappa values for ultrasonographic diagnosis was 0.732 with P value <0.001 which indicates good agreement with histopathology.
Authors and Affiliations
Beena Sebastian
Keywords
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