A Study on Characterization of Breast Lesions Using Sonomammography and Comparing with Histopathology
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Introduction: The changing lifestyle practices can lead to a higher number of cancer cases. Breast cancer is the most common cancer among women in India. It is very important to identify the palpable breast lump as benign or malignant. Ultrasonography is a commonly used screening imaging modality in breast lumps. The present study aims to find out the accuracy of sonomammography by comparing with histopathology. Materials and Methods: A descriptive study was conducted among female patients for one year. It included 75 female patients above 20 years of age with palpable breast lesions and bloody discharge from the nipple. Patients with advanced carcinoma, previously treated cases and patients with history of previous breast biopsy were excluded from the study. Designed as diagnostic test evaluation, sensitivity, specificity, positive predictive value and negative predictive value of the variables in differentiation was calculated comparing with histolopathological diagnosis. The features of ultrasonography was analyzed by Cohen’s Kappa for statistical agreement with histopathology. Results: With sonomammography, the sensitivity, specificity and accuracy obtained were 83.3%, 89.7% and 86.67% respectively for detection of malignancy. Discussion and Conclusion: Sonomammography is a very useful non-invasive imaging modality having high sensitivity and specificity in diagnosing breast lesions. This study shows that ultrasonography is useful in characterization of breast masses. The requirement of biopsy for breast masses can be reduced. The kappa values for ultrasonographic diagnosis was 0.732 with P value <0.001 which indicates good agreement with histopathology.
Authors and Affiliations
Beena Sebastian
Keywords
Related Articles
- EP ID EP486829
- DOI -
- Views 89
- Downloads 0
An Insight into Saliva as a Biomarker for Periodontal Disease
periodontal disease is a immune-inflammatory disease with varying degree of disease severity. It has been a challenge to determine biomarkers for screening and predicting the early onset of periodontal disease, evaluatin...
Transcerebellar Diameter: An Independent Marker for Estimation of Gestational Age
Cerebellum is a posterior cranial fossa structure, appears at the end of 5th week of gestational age. The cerebellum is easily visualised sonographically surrounded by petrous ridges and occipital bone. Measurement & dem...
Prospective Randomised Clinical Trial Study of Diclofenac Sodium 100mg Suppository and Trans Dermal Patch for the Duration of post Operative Analgesia in LSCS Patients Under Going Surgery under Lumbar Subarachnoid Block
Background: Post operative analgesia in continuation of lumbar subarachnoid blockade can be effected by several means. But use of non steroid anti inflammatory drugs in various forms is advantageous to the parturient and...
Comparative evaluation between Radiotherapy with cyclophosphamide and Radiotherapy alone for the palliative treatment of Non Small Cell Lung Carcinoma
Abstract
Diagnostic Outcome of Bone Marrow Aspiration– An Experience from Tertiary Care Hospital
Background: Bone marrow examination is a useful tool not only in determining the cause of disease but also helpful in establishing definitive diagnosis in most of the cases. It is relatively safe procedure which can be p...