A Study on Clinical and Laboratory Features of Spontaneous Bacterial Peritonitis in Chronic Liver Disease
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Objective: To determine the clinical and laboratory features, bacterial profile and antibiotic sensitivity pattern of Spontaneous Bacterial Peritonitis (SBP) in Chronic Liver Disease (CLD) patients presenting at a tertiary care hospital of Goa medical college hospital Study Design: Cross-sectional study. This study was done in department of medicine Goa medical college hospital, Panaji, Goa. Methodology: CLD patients with ascites were recruited from Goa medical college hospital. Basic demographics, symptoms and clinical signs of patients were recorded. Patients with the history of antibiotic use within last 3 days or any intra-abdominal source of infection were excluded. Diagnostic paracentesis was done for ascitic fluid detailed report (D/R) and culture. Blood sample was collected for total leukocyte count, serum proteins and billirubin levels. Results: Out of a total 100 CLD patients, 27 (27%) were diagnosed with SBP, Nine (33.7%) patients presented with classical SBP, 12 (44.4%) had culture negative neutrocytic ascites and 6 (22.2%) had bacterascites. Fever, abdominal tenderness and constipation were common in SBP patients. Ascitic fluid culture was positive in 15 (55.5%) patients. E. coli (63%) was the predominant pathogen followed by Enterococcus species (15%). Resistance was high against cephalosporins (78%) and fluoroquinolones (69.6%) and least against amikacin (13%) and meropenem (12%). Conclusion: Ascitic fluid D/R and culture together can lead to the accurate diagnosis of SBP and can guide for the right antibiotic choice as resistance to commonly prescribed antibiotic is common in such patients
Authors and Affiliations
Dr Archana Bhat
Keywords
Related Articles
- EP ID EP285110
- DOI -
- Views 98
- Downloads 0
A Rare Case of Autoimmune Hemolytic Anemia as a Presenting Complaint of HIV Infection
HIV patients commonly suffer from haematological complications and it can be because of infection per se or secondary to opportunistic infections and antiretroviral therapy. However overt autoimmune hemolytic anemia (AIH...
To study the clinical profile of severe plasmodium vivax malaria experience from tertiary care Centre in Agra
Severe malaria caused by P. vivax infection. Monoinfection by P. vivax can cause severe malaria as seen in P. falciparum. Aims and Objectives: To study clinical profile of plasmodium vivax patients admitted in tertiary c...
Comparison of volar locking compression plate Versus External Fixator in the Treatment of Distal Radius Fractures
Background: This is a prospective study was done to compare results of locking compression plate to external Fixator in treatment of fracture distal end of radius Methods: This study was conducted on 50 patients who were...
Dermatosis in New Born a Clinical Study
There are few studies on new born dermatosis in our country. The aim of present study is to know the incidence of cutaneous changes in our area. Influence of Sex, birth weight and duration of gestation on early neonatal...
Drugs Related Changes of Haemoglobin and CD4 Counts in HIV-Infected Patients on Antiretroviral Therapy
The present study examines the effects of antiretroviral therapy (ART) on two basic immunohaematological parameters over time. We performed a retrospective study of HIV-infected treatment-naïve patients starting a first...