A Study on Clinical Determinants and one year Follow-Up of Dementia and Mild Cognitive Impairment Following Ischemic Stroke

Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 10

Abstract

Background: Vascular cognitive impairment (VCI) is poised to become the silent epidemic of the 21st century and contribute significantly to mortality, disability, and decreased quality of life. . Aim: To investigate the frequency and clinical determinants of vascular dementia (VD) and Vascular mild cognitive impairment (VMCI) following ischemic stroke. The one year follow-up was done to assess the prognosis. . Materials and Methods: A prospective study was conducted among 100 consecutive patients aged ≥40 years with the diagnosis of ischemic stroke within previous 2 - 3 months. The subjects were be subjected to structured medical and neurological history based on review of all available hospital charts, interview of the subject and a knowledgeable informant, and a structured clinical, neurological, neuropsychological, and neuroradiological evaluation. Patients will be retested at 3, 6, and 12 months after stroke. . Results: 60% of stroke patients were diagnosed as VCI. 23 subjects were diagnosed as VD. The prevalence of VMCI was 37% and forty percent of the patients had no cognitive impairment. An annual conversion rate from ‘VMCI’ to ‘VD was 8%. The annual rate of deterioration from ‘No Cognitive Impairment’ to ‘VMCI’ was 10% . Conclusion: This study supports the high prevalence of dementia and mild cognitive impairment following stroke, especially in older individuals, and highlights the importance of cognitive reserve.

Authors and Affiliations

Murugapandian Nagarajan

Keywords

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  • EP ID EP529681
  • DOI -
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How To Cite

Murugapandian Nagarajan (2017). A Study on Clinical Determinants and one year Follow-Up of Dementia and Mild Cognitive Impairment Following Ischemic Stroke. Journal of Medical Science And clinical Research, 5(10), 29539-29548. https://europub.co.uk/articles/-A-529681