A Study on Clinical Presentation and Outcome of Concurrent Malaria and Dengue Infection from a Malaria Endemic Zone of North India
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 12
Abstract
This study has been done to differentiate clinical and biological parameter of co-infections from infections alone and to find out whether patients infected by both malaria and dengue were more severe than either infection alone. Material and Methods: All febrile adult patients (> 18 years of age) were investigated for malaria, dengue and other causes of fever. Patients of concurrent dengue and malaria (Group A) were compared with malaria mono-infection (Group B) and dengue mono-infection (Group C). Frequencies of alterations in clinical, biochemical, haematological parameters and outcome were determined in various groups. Data was analysed using appropriate statistical tests. Results: Out of these 340 patients, there were 52 (15.29%), 132 (38.82%), and 156 (45.88%) patients in Groups A, B, and C respectively. Prevalence of co-infection in our study was 25%. Features like prolonged fever (7.18+/- 3.91), severe anemia (23.07%) and respiratory distress (7.69%) were comparable to malaria mono-infection whereas features like bleeding manifestations(15.38%), frontal or retro-orbital headache (80%), arthralgia (15.38%) and / elevated haematocrit were more like dengue mono-infection. Conclusion: In endemic areas for dengue and malaria, prolonged fever, severe anemia and respiratory distress (in dengue patients) and bleeding manifestations, frontal or retro-orbital headache, arthralgia and / elevated haematocrit level (in malaria patients) should raise the suspicion of co-infection and since a high prevalence of co-infection was found in our geographical area. We recommend that all the patients suspected for dual infections should be treated concomitantly for dengue and malaria in malaria endemic areas
Authors and Affiliations
Rajendra Kumar Verma
Keywords
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