A Study On Clinico-Mycological Profile of Systemic Fungal Infection In Neonates: An Indian Perspective
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Objectives: To analyze clinical presentation and mycological profile of systemic fungal infection in neonates. Material and Methods: A hospital based prospective, observational study was done over a period of one year in the department of Pediatrics of Burdwan Medical College. The study included 254 neonateswho were admitted in newborn care unit (inborn and outborn) and were started on intravenous fluid. Results: Fungal culture was positive in 19 neonates (7.48%). The mean birth weight and gestational age of the neonates with positive fungal cultures were 1.539±0.593 kg and 33.368±2629 weeks respectively. Candida Parapsilosis was the most common organism in ˂1500 gm group whereas Candida albicans and Candida parapsilosis were mostly found in 1500-2499 gm group. The predominant presenting signs were related to the gastrointestinal system (68.4%). A significant difference was found in the repeat CRP between the two groups with the C.albicans group having a much higher CRP count (p=0.041). Conclusion- An idea of the organisms responsible for systemic fungal infection, help us to choose appropriate antifungals depending upon the resistance pattern.
Authors and Affiliations
Dr. Archan Sil, Dr. Amit Das, Dr. Mithun Chandra Konar
Keywords
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- DOI 10.9790/0853-160507117120.
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