A Study on Clinico Pathological Spectrum of Nephrotic Syndrome in Adult Patients in a Teaching Hospital in Eastern India
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 5
Abstract
Introduction: Nephrotic Syndrome is one of the important causes of end stage renal diseases in adult patients worldwide. Current research aimed to study prospectively the clinicopathological spectrum of glomerular disease pattern in adult nephrotic syndrome patients in a teaching hospital in Eastern India. Material and Methods: This non randomised prospective study was conducted on 72 indoor patients in the Department of Medicine presenting with nephrotic range of proteinuria (≥3 gm/24 hours) at a teaching hospital during the period of July 2016 to April 2018. Adult patients (≥18 years) with proteinuria ≥3gm/24 hours were included in the study whereas patients with coagulopathy, contracted kidney, drug induced and iatrogenic nephropathy, unilateral solitary kidney, acute pyelonephritis, vesico ureteric reflux and eGFR < 15 ml/ min/1.73m2 were excluded. Result: Out of 72 cases studied 48 were male mostly in the age group between 18 to 50 years presented with edema (100%),oliguria (8.3%), hypertension (36%), diabetes (25%), dyslipidemia (70%), hematuria (35%), anemia (65%), hypocomplimentemia (10%) and active urinary sediment (27.8%). TSH were normal in all cases and none was reactive to viral markers (HBsAg, Anti HCV antibody, HIV 1 and 2 antibody). 22% cases had renal insufficiency (Sr.Cr >1.4 mg/ dl). Conclusion: Primary Glomerulonephritides commonly MGN were found in majority of cases.
Authors and Affiliations
Anirban Sarkar, Faizanul Haque
Keywords
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