A study on incidence and severity of acute renal failure and its association with parasite density in hospitalised patients with falciparum malaria
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 10
Abstract
Aims of the study: To find out the incidence of acute renal failure in falciparum malaria and to correlate between the degree of parasitism at presentation with acute renal failure and its outcome in falciparum malaria.Methodology: Each patient with a history of fever, suggestive of severe malaria was subjected to peripheral blood smear examinations, up to 3 samples were examined or till positive and/or Pf antigen positive cases. The selected patients were then grouped according to the clinical features, laboratory parameters and were followed up for the outcome. Results: Out of the 50 cases of acute renal failure due to falciparum malaria, 21 had Parasite density <5% (42%), 13 had 5-10%(26%) and 16 had >10%(32%). Out of 21 cases of mild ARF 12 patients had parasite density<5% and 9 had >5%. Out of 29 cases of severe ARF 9 patients had parasite density<5% and 20 had >5%.Dialysis was done in a total of 31 cases (62%). In the severe form of acute renal failure.hemodialysis was required in 29 cases (58%), in the milder form of renal failure; only 2 cases (4%) required hemodialysis. Rests of the cases were managed by conservative treatment.Conclusion: Parasite Density has significant impact to predict the severity of renal failure,duration of hospital stays as well as the number of dialysis required. As the study was conducted with small number of cases, further study is necessary with large number of cases to arrive at a conclusion regarding the malady of acute renal failure in falciparum malaria.
Authors and Affiliations
Pinaki Mukhopadhyay, Biman Kumar Das, NM Biswas
Keywords
Related Articles
- EP ID EP276377
- DOI 10.17511/ijmrr. 2017.i10.06
- Views 141
- Downloads 0
Readdressing the role of therapeutic drug monitoring for antiepileptic drugs – A tertiary care hospital experience
Background: Therapeutic drug monitoring is a beneficial tool to supervise patients when they do not respond to a therapeutic dose. Inter individual variability in the concentration of an antiepileptic drug that produces...
Spectrum of MRI findings in traumaticknee
Introduction: Injuries to the intraarticular structures like menisci and cruciate ligaments are diagnosed with high sensitivity and specificity by MRI as compared with arthroscopy, which is still regarded as the gold sta...
T-Cell Lymphoma of Oral Cavity: A Case Report
Malignant lymphomas are heterogenous group of neoplasms of lymphoid tissues with different clinical courses and varied prognosis. Non-Hodgkin’s lymphoma (NHL) often presents at the extranodal sites of head and neck regio...
Tuberculosis of the distal ulna mimicking malignanacy - a rare case report
The tubercular involvement of the long bones of the extremities is very rare so, tuberculosis as a differential diagnosis is usually missed when a patient present with pain and swelling over long bones. The radiology is...
A study to assess the distribution of cystic and solid hepatic lesionson contrast enhanced helical computed tomography
Introduction: Focal liver lesions are defined as solid or liquid-containing masses foreign to the normal anatomy of the liver that may be told apart from the latter organ using imaging techniques. Material and Methods: T...