A study on meibomian gland disorders and lipid levels in north Indian population
Journal Title: International Journal Of Medical Science And Clinical Invention - Year 2018, Vol 4, Issue 8
Abstract
To study meibomian gland disorders (MGD) and lipid levels in north Indian population. Methods: This was a cross-sectional study. A total of 100 clinically diagnosed cases of MGD were included in the study. A detailed history using a Symptom Assessment in Dry Eye (SANDE) questionnaires was taken. Thorough clinical examination using Slit Lamp was performed to confirm the diagnosis of dry eye and for the probable etiology. For this, standard tests like Tear Film break-up time [TFBUT], Schirmer’s test, Phenol Red Thread test were employed. Patients found to have dry eye were evaluated further by slit-lamp biomicroscopy of the lid margins for posterior blepharitis and the degree of meibomian gland dysfunction, if any, was graded. After a complete ocular examination, they were allotted into the groups. Laboratory investigation that was performed in each patient included Serum Fasting Lipid Profile. Results: More than half (59%) of patients were above 45 years of age and 57% were males.Grade II severity of meibomitis was in more than one third of the cases (46%) followed by grade I (42%) and grade III (12%).Borderline cholesterol was in 55% of the cases who had grade II severity of meibomitis. High cholesterol level was found the 50% patients of grade III severity of meibomitis. However, this association was statistically insignificant (p>0.05). High TG was seen 53.5% and 30.2% of grade II and grade III severity of meibomitis. The association between TG level and severity of meibomitis was found to be statistically significant (p=0.0001). There was no significant (p>0.05) association of serum HDL level with severity of meibomitis. However, serum LDL level was found to be significantly (p=0.008) associated with severity of meibomitis. Conclusions: Patients with MGD with history of dyslipidemia may have undiscovered abnormal serum cholesterol, triglycerides and LDL levels.
Authors and Affiliations
Dr. Mohd Mobin , Dr. Pooja Kanodia ,Dr. Rubie Malhotra , Dr. Anurag Kumar Singh
Keywords
Related Articles
- EP ID EP315438
- DOI -
- Views 96
- Downloads 0
Mixed Ovarian Tumor with torsion ovary- A unique presentation
Ovarian torsion is one of the significant causes of acute abdomen in women. The presentation being vague, non specific and necessitates urgent diagnosis and surgical intervention to salvage the ovary. In the present case...
Prevalence of Hypertension in Patients with Chronic Obstructive Pulmonary Disease Attending Respiratory Medicine OPD
Hypertension is a common complication of chronic obstructive pulmonary disease (COPD); its prevalence is currently unknown. The objectives of the study were to provide data on the prevalence of hypertension among the COP...
Prevalence and causes of non-traumatic knee injuries in cyclists: a systematic review
Cycling has been a part of the modern Olympic Games since its inception in 1896 (1). In addition to professional sports practice, the popularity of using bicycles has been increasing for various reasons, including not on...
Transvaginal Sonographic Cervical Length Measurement as Predictor of Preterm Delivery
The present study entitled, “Transvaginal Sonographic cervical length measurement as predictor of Preterm delivery” was carried out on 150 cases of primiparas who attended the Govt. Medical College, Hospital, Nagpur. The...
Perinatal Outcome and Histopathological Evaluation of Placentas in Intrauterine Growth Restriction (IUGR) Pregnancies
Introduction: Intrauterine growth restriction (IUGR) is a condition in which fetus fails to achieve its inherent growth potential. It is the second most common cause of perinatal mortality and morbidity following prematu...