A STUDY ON METABOLIC SEIZURES IN A TERTIARY CARE PAEDIATRIC HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 15
Abstract
BACKGROUND This study is about the seizures caused by metabolic derangements in children. Metabolic seizures are important because many conditions are treatable and all of them have a risk for recurrence in the same family. Metabolic diseases can cause seizures by interfering with energy metabolism, changing osmolality or producing endogenous toxins. Long-term antiepileptic therapy may be needed in some metabolic seizures. Aims and Objectives- To study the demography, the causes and the management of metabolic seizures. MATERIALS AND METHODS This was a descriptive study. Data on children with metabolic seizures who were admitted in Institute of Child Health and Hospital for Children, Madras Medical College, Chennai between January 1, 2014 and December 31, 2017 were included in this report. Inclusion Criteria- Children up to 12 years including new-borns who were admitted with metabolic seizures in Institute of Child Health and Hospital for Children, Madras Medical College, Chennai between January 1, 2014 and December 31, 2017 were included in this report. Exclusion Criteria- Children with perinatal asphyxia and structural brain abnormalities were excluded from this study. RESULTS Out of the 35 patients diagnosed to have metabolic seizures, 21 children had hypocalcaemia, 4 had hypoglycaemia, 3 had biotin deficiency and 2 had hyperglycaemia and 5 had pyridoxine responsive seizures. CONCLUSION 1. In all children with refractory seizures, metabolic causes should be thought of. 2. Hypocalcaemia is the commonest cause of metabolic seizures in our study.
Authors and Affiliations
Viveka Saravanan Raju, Leema Pauline Cornelius
Keywords
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- EP ID EP414483
- DOI 10.14260/jemds/2018/431
- Views 92
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