A study on mutagen induced development of antibiotic resistance in some pathogenic bacteria
Journal Title: International Journal of Life Science - Year 2018, Vol 6, Issue 1
Abstract
The evolution of antibiotic resistance by pathogenic bacteria poses a major task for human health. Whereas it is unambiguous that natural selection promotes resistance-conferring mutations, our understanding of the response of the mutation rate to antibiotics is limited. Ever since effective antibiotic treatment was first introduced almost seventy years ago, it has been a notable success story and antibiotic treatment is without a doubt the single most important medical procedure or treatment ever invented as measured by the reduction in human morbidity and mortality. However, the present studies based on the industrial area like pharmaceutical, where chemical mutagen release as an effluent. Continue contact with chemical mutagen some microbes got changes and show different behavior when antibiotic used. The intensive contact of microbes with chemical mutagen resulted in antibiotic resistance among almost all major human pathogens, and the resulting loss of therapeutic options might generate a post-antibiotic era where present and future medical advances are negated. As resistant bacteria significantly reduce the possibilities of treating infections efficiently and boost the risk of complications and fatal outcome for patients with severe infections, it represents a major public health concern and economic problem both within the globally worldwide.
Authors and Affiliations
SK Kumbhakar, SS Chauhan
Keywords
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