A STUDY ON PLASMA BIOCHEMICAL PHENOMENA IN HYPOXIC-ISCHAEMIC ENCEPHALOPATHY CASES IN TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 14
Abstract
BACKGROUND Perinatal asphyxia can lead to hypoxic ischaemic encephalopathy (HIE). The mortality due to hypoxic ischaemic encephalopathy is as high as 28.8% and morbidity is 30% of surviving newborn due to hypoxic ischaemic encephalopathy. Aims and Objectives- To study the plasma biochemical phenomena in neonates with hypoxic ischaemic encephalopathy in relation with severity of HIE. MATERIALS AND METHODS It is a hospital-based prospective study done in tertiary care hospital in SCB Medical College Hospital and SVP PG Institute, Cuttack from November 2015 to October 2017. RESULTS The babies with perinatal asphyxia develop hyponatraemia, hypocalcaemia, hyperkalaemia, high serum urea and creatinine, high serum ALT, AST, ALP, decrease in serum albumin and increase in Prothrombin time in proportion to the severity of asphyxia. CONCLUSION A significant number of babies with birth asphyxia and deranged biochemical parameters either died or discharged with severe neurological sequelae. It can be concluded that deranged biochemical parameters are early indicators of poor outcome. Studies should be held on the effects of early correction of these metabolic derangements with their outcomes, so that it may invent a new horizon of treatment for birth asphyxia babies.
Authors and Affiliations
Leena Das, Mangal Charan Murmu, Bibhudutta Nayak
Keywords
Related Articles
- EP ID EP414332
- DOI 10.14260/jemds/2018/389
- Views 57
- Downloads 0
RISK FACTORS OF MORTALITY IN NEONATAL ILLNESS
BACKGROUND Infant Mortality Rate (IMR) is high in India. Identification of risk factors of mortality in neonatal illness is essential to reduce Neonatal Mortality Rate (NMR) and ultimately the IMR. AIM To id...
A COMPARATIVE STUDY OF RISK FACTORS OF CARDIOVASCULAR DISEASES IN YOUNG ADULTS WITH FAMILY HISTORY OF HYPERTENSION/DIABETES MELLITUS
BACKGROUND Non-communicable chronic diseases viz. diabetes mellitus, obesity, hypertension, cardiovascular diseases are assuming importance among the adult population in both developed and developing countries. Hypertens...
COMPARATIVE STUDY BETWEEN OPEN AND LAPAROSCOPIC APPENDECTOMY IN SILCHAR MEDICAL COLLEGE AND HOSPITAL
BACKGROUND Appendectomy is the most common operation performed by general surgeons. Open appendectomy has been the gold standard since its advent, but it is being gradually replaced by laparoscopic appendectomy. However,...
CLINICAL PROFILE AND OUTCOME OF PATIENTS WITH HYPONATREMIA AT TERTIARY CARE TEACHING HOSPITAL
BACKGROUND Hyponatremia is defined as a serum sodium concentration less than 135 mmol/L and is the most common electrolyte disorder encountered in clinical practice. MATERIALS AND METHODS This was a retrospective, descri...
LAPAROSCOPIC CHOLECYSTECTOMY UNDER SPINAL ANAESTHESIA- A PROSPECTIVE, RANDOMIZED COMPARATIVE STUDY BETWEEN INTRATHECAL FENTANYL AND CLONIDINE AS ADJUVANT WITH 0.5% HYPERBARIC BUPIVACAINE
BACKGROUND Laparoscopic cholecystectomy is usually done under general anaesthesia but in recent times, several studies have suggested that laparoscopic surgeries are safely done under spinal anaesthesia. To improve the q...