A Study on Precipitating Factors in Pemphigus
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 12
Abstract
Background: Pemphigus is the most common cause of morbidity and mortality among dermatological diseases even after treatment with immunosuppressants. There are not many studies on precipitating factors of pemphigus from India. Aims and Objectives: To identify the precipitating factors in pemphigus. Methodology: Study was conducted in 30 patients with clinically diagnosed pemphigus in the Department of Dermatology, in a tertiary care hospital in South India. Detailed history of the patients with emphasis on intake of any drugs, moderate or excessive intake of food items with acantholytic potential within one year prior to the onset of the disease were recorded. They were interrogated about history of any unaccustomed physical activity and excessive exposure to sunlight or any surgery in the recent past. Patients were asked whether any injury, burns or infection had occurred recently. Mental stress was assessed using Presumptive Stressful Life Events (PSLE) scale. Results: Precipitating factors noted were drugs (50%), infections (46.7%), sunlight (43.3%), physical stress (33.3%), mental stress (13.3%) intake of mango (13.3%), tea (10%), onion (10%) and chilly (10%). Statistical Analysis: All the data were entered in the proforma and were analysed using the statistical package for social science (SPSS) version 10. Conclusion: Mental stress and infections were found as statistically significant precipitating factors in pemphigus.
Authors and Affiliations
Dr Sheena Ann Simon
Minimal Hepatic Encephalopathy- The Invisible Challenge!
Minimal hepatic encephalopathy (MHE) is the earliest form of hepatic encephalopathy and can affect up to 80% of cirrhotic patients. MHE patients have normal mental and neurological status on standard clinical examination...
Comparison between GFR Values Obtained by CG-formula and DTPA Renography in Different Renal Disorders
Aim: The present study aims at comparing the glomerular filtration rate (GFR) values obtained by using Cockcroft-Gault (CG) formula and DTPA renography in different renal disorders. Material and method: This retrospectiv...
Efficacy of Peri-Operative Intercostal Nerve Blockade in Standard PCNL- A Prospective Cohort Study
Introduction and Aim: Percutaneous nephrolithotomy (PCNL) has become the GOLD standard for the management of renal calculi. But pain in the immediate post-op period especiallyin institutions where Standard PCNL is still...
Holmium Laser for Retrieval of Knotted Catheter- A Series of two Unique Cases
Catheter knotting, though rare, various techniques have been described for retrieval with significant morbidities such as general anesthesia, radiation exposure during fluoroscopy and hematuria. Thisreport demonstrates k...
Samprapti vivechan of Grudhrasi
According to Acharya Charaka definition of samprapti is, Vyadhi upalabdhee kaaraneshvakam tatha tatsvaroopam iti sampraapti | 1 i.e. Madhavacharya defines the term saprapti as follows. Rogasya smyak praapthi iti sampraap...