A Study on Prescribing Trends of Drugs in the Management of Bronchial Asthma: A Hospital-Based Study
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 1
Abstract
Background: Bronchial asthma is a common allergic condition with varied symptoms and necessitates the attention of the physician especially in acute attacks and poses a challenge to treat. Treatment to overcome the acute asthmatic episodes and control of chronic symptoms, nocturnal, and exercise-induced asthmatic symptoms leaves the physician in a dilemma. Pharmacologic management includes the use of control agents such as inhaled corticosteroids, long-acting bronchodilators (beta-agonists and anticholinergics), theophylline, and leukotriene modifiers. Relief medications include short-acting bronchodilators, systemic corticosteroids, and ipratropium. Aim of the Study: The aim is to study the current prescribing trends of specialists in a tertiary teaching hospital who treat patients’ bronchial asthma as primary or secondary physicians. Materials and Methods: A cross-sectional prospective study was conducted in the outpatient department (OPD) of a tertiary teaching hospital of Northern Kerala including the Departments of Medicine and Allied specialties over a period of 2 years. The specialties included were Medicine, Dermatology, Chest Diseases, and Psychiatry. 2,99,520 attended the OPD of the four specialty clinics of the hospital over a period of 2 years. 76,608 patients among these were positive history for different types of allergy. 31,194 patients (40.71%) among those patients with a history of various allergy disorders had a history of bronchial asthma. All the case records were accessed from the four specialty departments, and the demographic data were recorded for analysis including age, sex, occupation, history, family history, and drug prescription which includes the drugs prescribed dosage form and frequency. The percentage of all observed data was tabulated. Observations and Results: Salbutamol (β-agonists) + ipratropium bromide (anticholinergic) + levocetirizine + montelukast was the most commonly used combination as bronchodilator in 10287 (32.98%) of the patients. Formoterol + budesonide + fexofenadine + diphenhydramine combination was used in 5893 patients (18.71%). Doxophylline + fexofenadine combination was used in 4134 (13.25%) patients. Budesonide + montelukast + fexofenadine combination was used in 3256 (10.44%) patients. Etophylline + theophylline + levocetirizine combination was used in 2048 (9.97%) patients. Hydrocortisone + theophylline combination was found in 1947 (6.24%) patients. Methyl prednisolone + doxophylline + levocetirizine combination was used in 1001 (3.21%) patients. Dexamethasone + theophylline combination was used in 833 (2.67%) patients. Montelucast + doxophylline combination was used in 1.13% of the patients. Fexofenadine + diphenhydramine combination was used in 1.01% of the patients. Levocetirizine + montelukast combination was used in 0.39% of the patients. Conclusions: Combination therapy in the treatment of both acute and chronic types of bronchial asthma was found to be popular among the consultants of different specialties who treat the condition. The most common combination used in this study was salbutamol (β-agonists) + ipratropium bromide (anticholinergic) + levocetirizine + montelukast.
Authors and Affiliations
Iftekhar Ahmed Nazeer, Sabir Cholas
Keywords
Related Articles
- EP ID EP478610
- DOI -
- Views 119
- Downloads 0
Comprehensive Study of Acute Pancreatitis (Diagnosis, Disease Course, and Clinical Management): A Retrospective and Prospective Study
Background: Acute pancreatitis is an acute inflammatory process of the pancreas with variable involvement of other tissues or remote organ systems. Acute pancreatitis has widely variable clinical and systemic manifestati...
Prevalence of Gingival Diseases and Fluorosis in Children of Jammu City
Aim: The aim of the present study is to determine the prevalence of gingival diseases and fluorosis in children of Jammu City. Materials and Methods: A total of 1436 children (746 males and 690 females) who visited the D...
Fiber-reinforced Composite Resin Fixed Partial Denture to Restore Missing Anterior Teeth: A Case Report
Prosthetic dentistry constantly evolving as a result of innovative treatment solution based on new material, treatment technique, and technologies. The advent of fiber reinforced has further increased the potential uses...
Contemporary Views Regarding Prophylactic Third Molar Extraction among Dental Practitioners in Mumbai and Navi Mumbai City: A Cross-sectional, Questionnaire-based Survey
Background: The literature pertaining to third molar extractions is widespread and considered to be the most frequent procedure in oral and maxillofacial surgery. The prophylactic removal of asymptomatic impacted third m...
Association between Kidney Disease and Pre-diabetes by Plasma Glucose and Hba1c Levels
Introduction: Chronic kidney disease is recognized as a global health problem. Growing evidence links prediabetes to albuminuria and CKD and this association is a matter of concern worldwide nowadays.The study aims to fi...