A Study on Prevalence and Progression of Barrett’s Esophagus
Journal Title: IJSR-International Journal Of Scientific Research - Year 2016, Vol 5, Issue 8
Abstract
Introduction: The study was conducted to estimate the prevalence of Barrett’s esophagus in patients with reflux symptoms, to assess the prevalence of dysplasia in Barrett’s esophagus and to study the endoscopic and histopathological aspects of Barrett’s esophagus.Methods: A total of 79 patients were evaluated prospectively for symptoms compatible with GERD. In all cases, routine endoscopy and Prague Criteria of reporting of Barrett’s esophagus were performed. In each subject biopsy was taken and assessed histologically.Results: Endoscopically 35/79 had GERD, 28/79 had features of Barrett’s esophagus and 7/79 had islands of columnar epithelium. Histologically, intestinal metaplasia with goblet cells was present in 33(41.8%) and 8/33 (24.2%) had low grade dysplasia. Conclusion: The prevalence of Barrett’s esophagus was found to be 41.8% in patients with reflux symptoms and the prevalence of dysplasia in Barrett’s was found to be 24.2%. Endoscopic and histological features of Barrett’s esophagus were assessed in detail.
Authors and Affiliations
Aswathy Chandramohan, A. V. Rama devi, K. T. Shenoy, Sheela Vasudevan
Keywords
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