A study on sentinel lymph node biopsy in early breast carcinoma and its outcome on management
Journal Title: International Archives of Integrated Medicine - Year 2019, Vol 6, Issue 3
Abstract
Background: Breast cancer is a major health problem and was among the top three most common malignancies in the world. It is the most common cancer in women. It ranks fifth among the most common causes of cancer-related death worldwide, while it is the most frequent cause of cancer- related mortality in less developed countries. The aim of the study: The status of the lymph nodes in the axis is one of the key factors in patients with breast cancer. Histological examination of lymph nodes is the most accurate method for assessing lymph node metastasis. Materials and methods: A prospective study conducted on 20 patients in Government Royapettah Hospital in 2018. Early breast carcinoma with clinically axillary node negative and they was all undergoing sentinel lymph node biopsy and evaluated the outcome of the report with the postoperative histopathological report. Results: 12 cases were positive for sentinel lymph node biopsy and the postoperative report concluded the same. 8 cases were negative and hence proceeded with breast conservative surgery. Since only about 1/3rd of patients with clinically negative axilla had nodal metastases after post-operative histopathological examination of the ALND specimen, a significant number of patients would be at risk for the morbidity of ALND without benefiting from the procedure. Conclusion: Thus Sentinel lymph node biopsy alleviates the unnecessary need of axillary lymph node dissection in clinically node-negative patients.
Authors and Affiliations
B Santhi, Dr. Suganeswaran
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