A study on the effect of duration of Type 2 diabetes mellitus on nerve conduction velocity
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 12
Abstract
Background: Diabetic polyneuropathy, the most common type of neuropathy observed results from microvascular injury leading to damage of the nerve. Diabetic neuropathy depends on both duration as well as on the level of control of blood sugars. It depends more on the duration of diabetes. Aims and Objectives: This study was done to see the effect of duration of Type 2 diabetes on median nerve conduction velocity (NCV). Materials and Methods: A total of 100 subjects were taken, 50 patients of Type 2 diabetes mellitus with duration of 5 years or more and another 50 patients with duration of diabetes being <5 years. The entire recording was done using a four channel ADInstrument and compound muscle action potential were recorded using the LabChart software in both the groups. Results: We found that there was a significant (P < 0.05) decrease in the NCV among the diabetic population 5 years or more (45.01 ± 17.18) compared to the <5 years (51.55 ± 15.52). There was a non-significant change in the amplitude (P > 0.05) among the diabetic population 5 years or more (487.35 ± 60.74) compared to <5 years (536.19 ±63.88). There was a non-significant change in the distal latency (P > 0.05) among the diabetic duration of 5 years or more (0.00475 ± 0.0015) compared to <5 years of diabetes (0.004602 ± 0.0015). Conclusion: Thus, from our study we would like to conclude that there is a link between the duration of diabetes and NCV.
Authors and Affiliations
Chethan K, Sowjanya T
Keywords
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- EP ID EP497839
- DOI 10.5455/njppp.2018.8.0928920092018
- Views 68
- Downloads 0
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