A study on the effect of systemic hypertension on retinal nerve fibre layer thickness in West Bengal
Journal Title: Journal of the Indian Medical Association - Year 2019, Vol 117, Issue 4
Abstract
Retina is the innermost layer of the eyeball. The Retinal nerve fibre layer (RNFL) also known as the Stratum Opticum essentially consists of nonmyelinated axons of Ganglion cells, which in turn form the second order neurons of the visual pathway. It is to be noted in this regard that Glaucoma, a form of optic neuropathy, is characterized by optic nerve damage as evidenced by retinal nerve fibre layer defects. Several studies conducted worldwide have identified certain risk factors for glaucoma, systemic hypertension being one of them. Whether this factor decreases the retinal Nerve Fibre Layer Thickness in apparently normal individuals is yet to be established. The present work aims to study various aspects of this presumed determinant, that is, systemic hypertension on the retinal nerve fibre layer thickness in middle aged and elderly subjects of West Bengal and related risks of visualimpairment associated with this factor. An observational and cross-sectional study was undertaken to achieve the above objectives. Both eyes of 380 subjects of both sexes and aged above 40 years were examined and the results were recorded. Systemic blood pressure in all of them was recorded. Stratus Optical Coherence Tomograph (OCT) was used for Peripapillary Fast Retinal Nerve Fibre Layerthickness assessment of both eyes. Our study revealed that there is statistically significant reduction of Retinal Nerve Fibre Layer Thickness in hypertensives.
Authors and Affiliations
Alipta Bhattacharya, Swapan Bhattacharya, Gautam Bhaduri, Apala Bhattacharya, Soumya Swarup Chatterjee
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