A Study Showing Association between Hscrp and S. Cholesterol Level in Overweight and Obese Patients in Tertiary Care Centre In Gujarat, India
Journal Title: Journal of Research in Medical and Dental Science - Year 2017, Vol 5, Issue 3
Abstract
Obesity is rapidly growing health problem in both developed and developing countries. In adults, obesity is associated with hyperinsulinemia, insulin resistance, dyslipidemia, and vascular dysfunction. C - reactive protein (CRP), formerly considered solely as a biomarker for inflammation, is now viewed as a prominent partaker in endothelial dysfunction and atherosclerosis. The present study aims to establish correlation between elevated hscrp levels and elevated serum cholesterol levels in overweight and obese patients. The present study was undertaken at a tertiary care center in Gujarat, India for a period of 2 years. Inclusion criteria includes healthy males and females more than 18 years with body mass index ≥ 25kg/m2 whereas all the comorbidities like diabetes mellitus, hypertension, stroke, coronary artery disease is excluded. There was statistically significant positive correlation between elevated s. cholesterol level and HSCRP level (elevated s. cholesterol: normal s. cholesterol ratio of HSCRP is 2.96: 1.68, z value 5, p value < 0.0012). Data shows that there is more risk of future coronary events when there is combined elevation of s. cholesterol and HSCRP, but there may also be risk of future atherosclerosis and other coronary events when s. cholesterol is normal and HSCRP is elevated, as HSCRP is surrogate marker of inflammation and indirect predictive risk factor for atherosclerosis and other coronary events.
Authors and Affiliations
Varshit Hathi, Hiren Makwana
Keywords
Related Articles
- EP ID EP341972
- DOI -
- Views 131
- Downloads 0
A Study Showing Association between Hscrp and S. Cholesterol Level in Overweight and Obese Patients in Tertiary Care Centre In Gujarat, India
Obesity is rapidly growing health problem in both developed and developing countries. In adults, obesity is associated with hyperinsulinemia, insulin resistance, dyslipidemia, and vascular dysfunction. C - reactive prote...
Effect of insertion angles and reusing procedure on mini-screws’ mechanical properties
Retrieving mini-screw reduces treatment cost. However, one notable factor in this issue could be insertion angle. This study evaluates influence of insertion angles (50 and 90) and reusing procedure on mechanical propert...
Significance of Effect of Metformin on Cancer Stem Cells – “Need of an Hour” in oral cancer
Oral cancer is a life-threatening disease. Advanced therapeutic approaches are still insufficient to improve the prognosis. Effect of Metformin on cancer stem cells (CSCs) provides promising future. Research on diverse m...
An overview of malignancy cases reported on histopathology over a Span of 5 years (2011-2015) at Terna Medical College, Nerul, Navi Mumbai
The incidence and burden of cancer is huge and is set to rise. Cancer kills more people on a global scale than AIDS, malaria and TB combined, hence proving to be the most fatal disease for our Society. The aim of this st...
The Relatioships Among Leptin, Resistin, Visfatin, Transforming Growth Factor (TGF)-β Level and The Severity Grade of Osteoarthritis in Osteoarthritis Patients with Obesity
Obesity is risk factor for osteoarthritis (OA), that increased production of adipokine from adipocyte, such as leptin, adiponectine, resistin and visfatin. Some studies showed there was a relationship between adipokine l...