A Study to Assess Correlation of Adenosine Deaminase Activity with Different Predictors and Parameters of Diabetes and Obesity
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 12
Abstract
Introduction: Obesity is a complex disorder that involves some degree of over-consumption1 coupled with a metabolic derangement. As ADA has been putatively associated with inflammation, and adipose tissue inflammation is the hallmark of insulin resistance in obese T2DM patients. Our study attempted to evaluate the role of serum ADA in T2DM subjects. Methods: This observational cross sectional study was conducted in the Department of Biochemistry at MGM Medical College and MY Hospital. All the patients and controls were clinically examined and routine biochemical tests were analyzed for all subjects. Result: Correlations of ADA with different predictors of obesity and diabetes were calculated. ADA was found to be positively correlated with FBS, HBA1C, Insulin, Leptin and HOMA IR whereas negative correlation was found between ADA and Adiponectin. Conclusion: This is very much evident through this study that ADA may be treated as prognostic predictor of diabetes either linked to obesity or not.
Authors and Affiliations
Dr Neeraj Gour
Keywords
Related Articles
- EP ID EP519539
- DOI -
- Views 43
- Downloads 0
A study to compare the efficacy, safety & economy of oral iron chelators in patients with Thalassaemia major
Background: Thalassemia is an inherited impairment of hemoglobin production, in which there is partial or complete failure to synthesize a specific type of globin chain. It is characterized by ineffective erythropoesis a...
Gender independent Monitoring of Hepatotoxicity with the help of Hepatic Aminotransferase Level as a Prognostic & Tolerance tool-DOTS Patients
Aims & Objectives: To study the status of liver functions in patients of multidrug resistant tuberculosis. To asses the prevalence of hepatotoxicity in these patients. To compare and correlate this hepatotoxicity with po...
Clinical Profile of Mortality due to fever with Thrombocytopenia during an Epidemic
Introduction: Many of the acute infective diseases which present as febrile thrombocytopenia during an epidemic have overlapping clinical profile and many of them may not have a definite diagnosis even at the time of pat...
Post Traumatic Solitary Giant Synovial Osteochondroma of Elbow
Primary synovial chondromatosis represents a relatively rare benign neoplastic process which shows hyaline cartilage nodules in the subsynovial tissue of a joint, tendon sheath, or bursa. It commonly occurs within joints...
Effect of Health Education Intervention on Knowledge and Practice about reproductive health among Adolescent Female Students
Adolescence is the most important period of one’s Life. It is a fundamental component of an individual's overall health status and a central determinant of quality of life. Aims of the study: The aim of this study was to...