A study to assess the effect of Intravenous iron sucrose therapy in pregnant women with moderate anaemia
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 11
Abstract
Background: Iron deficiency anaemia (IDA) is the most common nutritional deficiency in pregnancy. Prophylactic oral iron is recommended during pregnancy to meet the increased requirement. In India, women become pregnant with low baseline haemoglobin level resulting in high incidence of moderate to severe anaemia in pregnancy where oral iron therapy cannot meet the requirement. Pregnant women with moderate anaemia are to be treated with parenteral iron therapy. Objectives: This study was undertaken to evaluate the response and effect of intravenous iron sucrose given to pregnant women with IDA. Methods: This study was conducted in between January 2010 to December 2011. One hundred pregnant women with haemoglobin between 7-9 gm% with diagnosed iron deficiency attending antenatal clinic were given intravenous iron sucrose in a dose of 200 mg twice weekly schedule after calculating the dose requirement. Result: Mean heamoglobin raised from 7.63 to 11.20 gm% (P<0.001) after eight week of therapy. There was significant rise in serum ferritin levels (from 11.2 to 69 μg/l) (P<0.001). Reticulocyte count increased significantly after two week of starting therapy (from 1.5 to 4.6). Other parameters including serum iron levels and red cell indices were also improved significantly. No major side effects or anaphylactic reactions were noted during study period. Conclusions: Parenteral iron therapy was effective in increasing haemoglobin, serum ferritin and other haematological parameters in pregnant women with moderate anaemia. Intravenous iron sucrose can be used as it can replace intramuscular therapy due to injection related side effects.
Authors and Affiliations
Sonali Gaikwad, Dhruvendra Pandey, Rahul Rokade, Sugandha Sirohi
Keywords
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