A study to correlate level of thrombocytopenia with dengue seropositive patients and frequency of bleeding pattern
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 1
Abstract
Thrombocytopenia is the major determinant of severity of dengue infection but bleeding may present with any number of platelet count among thrombocytopenic patients. The main objective in this study to correlate level of thrombocytopenia with dengue seropositive patients and frequency of bleeding pattern. The materials and methods in this prospective study, 263 patients were enrolled as dengue fevers were analyzed further with platelet count and various bleeding manifestations. In results the Petechiae (27.9%) was the most common bleeding manifestations followed by GI bleeding and gum bleed seen in 12.9% patients equally. Most of the patients (86.31%) showed thrombocytopenia but all of them were not presented with bleeding tendencies. 100 out of 135 i.e. 67% patients of dengue fever, 118 (120) Dengue hemorrhagic fever and 7 (8) dengue shock syndrome patients were thrombocytopenic (platelet count <1, 50,000 per cubic mm).Majority of patients with bleeding manifestations had moderate thrombocytopenia (20,000 – 50,000 mm3). Thrombocytopenia increase with clinical severity of dengue infection and even moderate thrombocytopenia can also be seen among classical dengue fever. Frequency of bleeding pattern was not correlated with severity of thrombocytopenia as majority of cases were in moderate range thrombocytopenia i.e. 20,000 – 50,000 mm3. Keywords: DEN, DHF, DSS, NS1, SD, ELISA, PT.
Authors and Affiliations
Richa Giri, Dr Kanhaiya Agarwal, Dr Shivendra Verma, Dr Rajendra Verma, Dr Lipok
Keywords
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