A Study to Determine Impact of Non-Compliance to Secondary Prophylaxis On Survivors of Acute Myocardial Infarction Post Discharge
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Background: Coronary artery disease is the one of the leading cause of mortality and morbidity in India1 and has huge economic burden. Non-adherence to cardiovascular medications is pandemic and a leading risk factor for the treatment failures and poor outcomes. This study was undertaken with to determine if any relation exists between degrees of adherence to pharmacotherapy amongst survivors of acute myocardial infarction to their outcome at 6 month follow up. Methods: This study was carried out in the Department of Medicine, M.G.M. Medical College and M.Y. Hospital Indore from November 2013 to October 2014. We included 100 consecutive patients of myocardial infarction admitted to intensive coronary care unit. All patients or legally acceptable representative provided written informed consent for participation. The research protocol and informed consent form was approved by The Institutional Review Board. Results: All 100 patients were followed out of 67 patients who were compliant to prescribed therapy, 78% had no complication while 22% developed various complications over a period of 6 month follow up. Out of 33 patients who were noncompliant, 37% had no complications while 63% developed various complications. The patients who were noncompliant to prescribed therapy had more adverse clinical events in comparison to those who were complaint to prescribed therapy. Conclusions: Patients who were non adherent to prescribed pharmacotherapy had three times more adverse cardiovascular outcomes in comparison to those who were adherent to prescribed therapy. Adherence to the secondary prophylaxis is crucial to prevent adverse cardiovascular complications and needs to have multimodal approach to tackle non adherence.
Authors and Affiliations
Yashwant Panwar, Akhilesh Shroti, Anil Bharani
Keywords
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- EP ID EP540267
- DOI 10.21276/ijmrp.2018.4.2.083
- Views 116
- Downloads 0
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