A Systematic Review of Metabolite Profiling in Diabetic Nephropathy
Journal Title: Journal of Endocrinology and Diabetes - Year 2015, Vol 2, Issue 3
Abstract
In recent years, the incidence of diabetic nephropathy (DN) is in sharply rising trend. It is a great challenge for health care professionals to prevent the DN.As the tool of modern bioinformatics research, metabonomics is of great significance for the early diagnosis of disease. In order to have a discussion about this, we conducted a systematic search of MEDLINE (PubMed) up using the key term combinations of 'metabolomics' and 'metabonomics' with 'diabetic nephropathy'. Finally we selected 18 articles. These researches help us to find more sensitive biomarkers to contribute to the diagnosis and therapeutic treatment of DN at an early phase and provide some ideas for the research of DN. This systematic review mainly summarized the current state of research on differential biomarkers of DN and discussed the clinical relevance of metabolomics in the prediction, diagnosis and management of DN.
Authors and Affiliations
Lin Zhang, Xiaotian Liu, Chao Liu, Libin Zhan
Keywords
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- EP ID EP333227
- DOI 10.15226/2374-6890/2/3/00127
- Views 110
- Downloads 0
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